Results 41 to 50 of about 462,525 (261)
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
The cemented coal gangue backfill (CGB) in coal mining is normally made of gangue (particle size of 0–15 mm), fly ash, cement, and water. In this study, the effects of the weight content (ranging from 20% to 60%) of fine gangue (0–5 mm) on the ...
Tingye Qi +5 more
doaj +1 more source
Analysis of the Influence of Mud Content on the Engineering Characteristics of Sand Sulfate Saline Soil [PDF]
In order to study the influence of mud content on salt swelling and mechanical properties of sand sulfate soils, sand sulfate soils with different fine-grained soil content were manually configured.
ZHANG Shasha +3 more
doaj +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
Climate change has a significant negative impact on agriculture and food production. This trend requires technological development and the adaptation of new technologies in both the grapevine production and winemaking sectors.
Diána Ágnes Nyitrainé Sárdy +2 more
doaj +1 more source
Level of anthocyanin content in flush is different between fine flavor cocoa and bulk cocoa. This study was aimed to determine the potential of anthocyanin and chlorophyll content in flush as one of the selection indicator for fine flavor cocoa.
Indah Anita Sari +6 more
doaj +1 more source
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effect of Fine Fractions on Engineering Properties of Sandy Soils in Gamo Zone, Southern Ethiopia
The current study examines the effect of fine content (passing a 75µm sieve) on the engineering properties of sandy soil. Sand samples were collected from the Kulfo riverside(site one), Hamasa(site two), Mirab Abaya(site three), and the sand samples were
Paulos Sisay Shido +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

