Results 61 to 70 of about 2,307,751 (295)

Experimental research on compaction characteristics of gap-graded coarse-grained soils

Yantu gongcheng xuebao, 2019
The gap-graded coarse-grained soils are commonly encountered in geoengineering applications. However, their compaction characteristics remain unclear. By conducting a series of compaction tests, several influencing factors are studied.
YU Ji-du , LIU Si-hong , WANG Tao, WEI Hao
doaj   +1 more source

Attention-Based LSTM for Psychological Stress Detection from Spoken Language Using Distant Supervision

, 2018
We propose a Long Short-Term Memory (LSTM) with attention mechanism to classify psychological stress from self-conducted interview transcriptions.
Fung, Pascale, Kampman, Onno Pepijn, Winata, Genta Indra   +2 more
core   +1 more source

Genetic recombination is targeted towards gene promoter regions in dogs [PDF]

, 2013
The identification of the H3K4 trimethylase, PRDM9, as the gene responsible for recombination hotspot localization has provided considerable insight into the mechanisms by which recombination is initiated in mammals.
Adam Auton, Adam R Boyko, Carlos D Bustamante, J Kim Holloway, Jeffrey Kidd, Jessica J Hayward, John M Greally, Julie Nadel, Jun Wang, Jun Wang, Kyle Oliveira, Paula E Cohen, Ying Rui Li   +12 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Assessing the Applicability of a Partial Alcohol Reduction Method to the Fine Wine Analytical Composition of Pinot Gris

Foods
Climate change has a significant negative impact on agriculture and food production. This trend requires technological development and the adaptation of new technologies in both the grapevine production and winemaking sectors.
Diána Ágnes Nyitrainé Sárdy, Péter Bodor-Pesti, Szabina Steckl   +2 more
doaj   +1 more source

XML data integrity based on concatenated hash function [PDF]

, 2009
Data integrity is the fundamental for data authentication. A major problem for XML data authentication is that signed XML data can be copied to another document but still keep signature valid. This is caused by XML data integrity protecting.
Liu, B, Lu, J, Yip, YJ
core  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Large-scale direct shear tests on silty sand gravel soil

Yantu gongcheng xuebao
By changing the content of particles below 5 mm in the mixture, the indoor direct shear tests on silty sand gravel soil are carried out. The shear characteristics of gravel soil and the variation laws between shear strength parameters and gravel content ...
HAN Huaqiang 1, 2, LI Dongbing 1, OUYANG Yanqing 3, SUN Zhenyuan 1, FU Hua 1, 2
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source