Results 81 to 90 of about 163,887 (300)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Cognitive and motor disturbances in depression: insights from comprehensive behavioral assessments

open access: yesFrontiers in Psychiatry
BackgroundDepression affects not only mood and reward processing, but also motor and cognitive functioning, leading to psychomotor disturbances crucial for diagnosis, prognosis, and treatment.
Ioanna Douka   +8 more
doaj   +1 more source

The influence of motor imagery on the learning of a fine hand motor skill

open access: yesExperimental Brain Research, 2016
Motor imagery has been argued to affect the acquisition of motor skills. The present study examined the specificity of motor imagery on the learning of a fine hand motor skill by employing a modified discrete sequence production task: the Go/NoGo DSP task.
Sobierajewicz, Jagna   +4 more
openaire   +2 more sources

Oral Motor Deficits in Speech-Impaired Children with Autism

open access: yes, 2013
Absence of communicative speech in autism has been presumed to reflect a fundamental deficit in the use of language, but at least in a subpopulation may instead stem from motor and oral motor issues. Clinical reports of disparity between receptive versus
Cherian, R   +17 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Fine motor skills predict expressive, but not receptive, language abilities in minimally verbal autistic adults

open access: yesFrontiers in Language Sciences
IntroductionPrevious research suggests that the motor system plays an important role in spoken language development for children and adolescents with autism spectrum disorder (ASD).
Meredith Pecukonis   +18 more
doaj   +1 more source

Refocusing on Fine Motor: Increasing Accessibility to Fine Motor Resources in a Virtual World

open access: yes, 2021
This capstone project was designed to increase resources and accessibility to trusted fine motor activities and exercises. This was accomplished through design of an online interface that aimed to serve students who fell within tier one and tier two of ...
McLey, Robin R
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Beyond words: an investigation of fine motor skills and the verbal communication spectrum in autism

open access: yesFrontiers in Psychiatry
IntroductionThis study investigated the associations between fine motor skills and expressive verbal abilities in a group of 97 autistic participants (age 8-17, mean=12.41) and 46 typically developing youth (age 8-17, mean=12.48).MethodsParticipants ...
Marian Simarro Gonzalez   +6 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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