Results 71 to 80 of about 2,358,245 (262)

Relationship Between Executive Function and Motor Skills in Early Childhood: A Longitudinal Study

open access: yesBehavioral Sciences
This longitudinal study investigates the dynamic interplay between Executive Function (EF), gross motor (GM), and fine motor (FM) skills in early childhood, specifically examining their mutual influences over a three-year period.
Bo Lyu, Zhixuan Liu, Xiaozi Gao
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Motor carrier news

open access: yes, 1996
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.May 1996-Title from captionMode of access: Internet from the

core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

menjelajahi permainan tradisional : bagaimana dampaknya pada motorik anak : Tinjauan Literatur

open access: yesIndonesian Journal of Physical Education and Sport Science
Tujuan studi. Penelitian ini bertujuan untuk mengeksplorasi dampak permainan tradisional terhadap perkembangan motorik anak, serta untuk mengidentifikasi nilai pendidikan yang terkandung di dalamnya. Bahan dan metode.
Baharuddin Hasan   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Coordinación grafoperceptiva: incidencia en el desarrollo de la motricidad fina en niños de 5 a 6 años de edad

open access: yesCiencia UNEMI, 2017
This paper aims to determine the incidence of grapho-perceptive coordination in the proper development of daily school activities of children 5-6 years of age in a Basic Education institution in the canton Milagro, Ecuador.
Ramírez-Aguirre, Gardenia   +4 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

IQ discrepancy differentiates levels of fine motor skills and their relationship in children with autism spectrum disorders

open access: yes, 2018
Tzu-Ying Yu,1 Willy Chou,2,3 Julie Chi Chow,4 Chien-Ho Lin,5 Li-Chen Tung,2,6 Kuan-Lin Chen7,8 1Department of Occupational Therapy, College of Medicine, I-Shou University, Kaohsiung, 2Department of Physical Medicine and Rehabilitation, Chi-Mei Medical ...
Chou W   +5 more
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