Results 71 to 80 of about 163,887 (300)
Danse-doigts, a Fine Motor Game
CoRR, 2016 This paper describes the design, implementation and testing of "Danse-doigts", an edutainment therapeutic application for hemiplegic children. The objective of this program is twofold. Firstly, to allow them to train their fine motor skills on tablet.
Susini, Jean-Ferdinand +3 more
openaire +3 more sources
Corticomotor excitability during precision motor tasks [PDF]
, 2009 The aim of this preliminary study was to investigate motor cortex (cortical) excitability between a similar fine visuomotor task of varying difficulty.
Pearce, Alan J
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Toddlers’ Fine Motor Milestone Achievement is Associated with Early Touchscreen Scrolling
Frontiers in Psychology, 2016 Touchscreen technologies provide an intuitive and attractive source of sensory/cognitive stimulation for young children. Despite fears that usage may have a negative impact on toddlers’ cognitive development, empirical evidence is lacking.
Rachael Bedford +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Examining the Purdue Pegboard Test for Occupational Therapy Practice
Open Journal of Occupational Therapy, 2015 Background: Occupational therapy ethics require that therapists use current assessment tools that provide useful comparison data. When an assessment only has normative data that is more than 40 years old, it cannot be considered current. The purpose of
Debra Lindstrom-Hazel +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Association between reported ADHD symptom and motor development delay in preschool children
Frontiers in PediatricsObjectiveTo explore whether the motor developmental level is associated with the attention deficit/hyperactivity disorder (ADHD) symptoms severity reported by parents in preschool children.MethodsPreschool children aged 4–6 years old with the chief ...
Zhijun Cui +4 more
doaj +1 more source
Fine Motor Matters - A Plan to Improve Fine Motor Skills at the Early Childhood Level
, 2022 Fine motor skills at the early childhood level have been well-researched. The early childhood years have proven to be vital years of growth and development in a child\u27s life.
Slater, Natasha
core