Results 111 to 120 of about 353,518 (312)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Optimizing the operating conditions of gold elution and electrowinning for Tau Lekoa stream at Kopanang gold plant [PDF]

open access: yes, 2008
The final gold product of Tau Lekoa mine has a low fineness. This is caused by high concentration of bases metals in the reefs. Some of these base metals together with gold are leached with cyanide and are loaded into carbon. If not adequately controlled,
Lunga, Alfred Lodi
core  

A Fine Meteor [PDF]

open access: yesNature, 1889
A FINE meteor was visible here to-night at 6.36 p.m. It fell perpendicularly almost due north-north-east, disappearing about 20° above the horizon, and was then as nearly as possible of the brilliancy and colour of Venus, which was shining in the southwest at the time.
openaire   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Small scale production and storage quality of dry-milled degermed maize products for tropical countries [PDF]

open access: yes, 2009
The present study aims to propose a comprehensive appropriate technological package for small-scale processing of maize flour, which meets consumer demand for quality and achieves extended shelf life.
Davo, Agbéwonu Kosi   +2 more
core  

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Some measurements of the dynamic and static stability of two blunt-nosed, low-fineness- ratio bodies of revolution in free flight at mequal4 [PDF]

open access: yes
Dynamic and static stability of two blunt nosed low fineness ratio bodies of revolution in free flight ...
Short, B. J., Sommer, S. C.
core   +1 more source

Equivariant smoothing of piecewise linear manifolds

open access: yes, 2017
We prove that every piecewise linear manifold of dimension up to four on which a finite group acts by piecewise linear homeomorphisms admits a compatible smooth structure with respect to which the group acts smoothly.
Lange, Christian
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Fine-Tuning is Fine, if Calibrated

open access: yes
Fine-tuning is arguably the most straightforward way to tailor a pre-trained model (e.g., a foundation model) to downstream applications, but it also comes with the risk of losing valuable knowledge the model had learned in pre-training. For example, fine-tuning a pre-trained classifier capable of recognizing a large number of classes to master a ...
Mai, Zheda   +10 more
openaire   +2 more sources

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