Results 51 to 60 of about 130,116 (165)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Gender Determination using Fingerprint Features [PDF]

open access: yes, 2008
Several previous studies have investigated the gender difference of the fingerprint features. However, regarding to the statistical significance of such differences, inconsistent results have been obtained. To resolve this problem and to develop a method
Chang, Yung-Hsien   +5 more
core   +1 more source

TEST: A Tropic, Embodied, and Situated Theory of Cognition [PDF]

open access: yes, 2013
TEST is a novel taxonomy of knowledge representations based on three distinct hierarchically organized representational features: Tropism, Embodiment, and Situatedness.
Fischer, Martin   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Differential Development of Children’s Understanding of the Cardinality of Small Numbers and Zero

open access: yesFrontiers in Psychology, 2018
Counting and the understanding of cardinality are important steps in children’s numerical development. Recent studies have indicated that language and visuospatial abilities play an important role in the development of children’s cardinal knowledge of ...
Silvia Pixner   +3 more
doaj   +1 more source

Effect of Finger Gnosis on Young Chinese Children’s Addition Skills

open access: yesFrontiers in Psychology, 2020
Evidence has revealed an association between finger gnosis and arithmetic skills in young Western children, however, it is unknown whether such an association can be generalized to Chinese children and what mechanism may underlie this relationship.
Li Zhang, Wei Wang, Xiao Zhang
doaj   +1 more source

Pointing as an Instrumental Gesture : Gaze Representation Through Indication [PDF]

open access: yes, 2013
The research of the first author was supported by a Fulbright Visiting Scholar Fellowship and developed in 2012 during a period of research visit at the University of Memphis.Peer reviewedPublisher ...
Cappuccio, Massimiliano L.   +2 more
core  

ATLAST detector needs for direct spectroscopic biosignature characterization in the visible and near-IR [PDF]

open access: yes, 2015
Are we alone? Answering this ageless question will be a major focus for astrophysics in coming decades. Our tools will include unprecedentedly large UV-Optical-IR space telescopes working with advanced coronagraphs and starshades.
Bolcar, Matthew R.   +8 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Playing Reading, Using Hands: Which Activities are Linked to Number-Space Processing in Preschool Children?

open access: yesPsychology of Language and Communication, 2017
Literate subjects from Western cultures form spatial-numerical associations (SNA) in left-to-right direction, which follows their reading habits. In preliterate children, sources of SNA directionality are more disputable.
Patro Katarzyna, Haman Maciej
doaj   +1 more source

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