Results 61 to 70 of about 35,346 (262)

A Database for Learning Numbers by Visual Finger Recognition in Developmental Neuro-Robotics

Frontiers in Neurorobotics, 2021
Numerical cognition is a fundamental component of human intelligence that has not been fully understood yet. Indeed, it is a subject of research in many disciplines, e.g., neuroscience, education, cognitive and developmental psychology, philosophy of ...
Sergio Davies, Alexandr Lucas, Alexandr Lucas, Carlos Ricolfe-Viala, Alessandro Di Nuovo   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Stimulating numbers: signatures of finger counting in numerosity processing

, 2018
Finger counting is one of the first steps in the development of mature number concepts. With a one-to-one correspondence of fingers to numbers in Western finger counting, fingers hold two numerical meanings: one is based on the number of fingers raised ...
Oliver Lindemann, Fischer, Martin H. (Prof. Dr.), Martin H. Fischer, Sixtus, Elena (Dr. phil.), Elena Sixtus, Lindemann, Oliver   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Finger-counting in the Upper Palaeolithic

, 2021
Upper Palaeolithic hand stencils at Cosquer Cave have been interpreted as forming a numeric code. The present analysis examined ‘digits’ at Cosquer and Gargas from the perspectives of modern ethnography, shared cognitive functioning and human hand anatomy, concluding that correspondences between the 27,000-year-old hand stencils and modern finger ...
openaire   +3 more sources

Sex and lateral asymmetry of the finger ridge-count

Annals of Human Biology, 1977
In a sample 719 individuals, the bimanual difference in ridge-count (right minus left) differed only slightly between the two sexes, the mean difference being 0-621 (females minus males). This is not statistically significant, but further evidence suggests that this difference may be real.
J, Rostron, U, Mittwoch
openaire   +2 more sources

A hand full of numbers: a role for offloading in arithmetics learning?

Frontiers in Psychology, 2011
Finger counting has been associated to arithmetic learning in children. We examined children with (n = 14) and without (n = 84) mathematics learning difficulties with ages between 8 to 11 years.
Annelise Júlio Costa, Júlia Beatriz Lopes Silva, Júlia Beatriz Lopes Silva, Pedro ePinheiro-Chagas, Pedro ePinheiro-Chagas, Helga eKrinzinger, Jan eLonnemann, Jan eLonnemann, Jan eLonnemann, Klaus eWillmes, Guilherme eWood, Vitor Geraldi Haase, Vitor Geraldi Haase, Vitor Geraldi Haase   +13 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A genetical analysis of diversity and asymmetry in finger ridge counts [PDF]

Heredity, 1982
The genetics of asymmetry and diversity of finger ridge counts in man has been examined by jointly regressing the individual counts of each hand on to the mean values summed over left and right hands in a sample of twins. The resulting asymmetry terms are largely under environmental control but with a small significant genetic component.
MARTIN, NG, JINKS, JL, BERRY, HS, LOESCH, DZ   +3 more
openaire   +4 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source