Results 101 to 110 of about 23,963 (194)

Effects of Crocin on Brain Neurotrophins, Cognition, Balance and Pain in Toxic-Induced Demyelination Model

Acta Neurologica Taiwanica
Objective: The purpose of this study was to investigate the effects of Crocin on brain neuroterophins, cognition, sensory and motor dysfunction and compare to fingolimod effects in toxic-induced demyelination with Ethidium Bromide (EB) in female Wistar ...
Rouholah Fatemi, Hadi Fathi Moghaddam, Yaghoub Farbod, Roya Bigtashkhani   +3 more
doaj   +1 more source

Extensive Multiple Sclerosis Reactivation after Switching from Fingolimod to Rituximab

Case Reports in Neurological Medicine, 2018
During treatment with fingolimod, B cells are redistributed from blood to secondary lymphoid organs, where they are protected from the effect of anti-CD20 and other cell-depleting therapies.
Trygve Holmøy, Øivind Torkildsen, Svetozar Zarnovicky   +2 more
doaj   +1 more source

Clinical and radiological implications of subpotent generic fingolimod in multiple sclerosis: a case series

Therapeutic Advances in Neurological Disorders
An expansion in the availability of generic specialty disease modifying therapies (DMTs) for treatment of multiple sclerosis (MS) has increased recently.
Darin T. Okuda, Lauren M. Tardo, Crystal M. Wright, Shanan B. Munoz, Tom G. Punnen, Mahi A. Patel, Tatum M. Moog, Katy W. Burgess   +7 more
doaj   +1 more source

The spingosine-1-phosphate analogue FTY720 impairs mucosal immunity and clearance of the enteric pathogen Citrobacter rodentium [PDF]

, 2012
The sphingosine-1-phosphate (S1P) analogue, FTY720, is therapeutically efficacious in multiple sclerosis and in the prevention of transplant rejection.
Hall, Lindsay J., Hurley, Grainne, MacSharry, John, Melgar, Silvia, Murphy, Carola T., Nally, Kenneth, Quinlan, Aoife, Shanahan, Fergus   +7 more
core  

Natalizumab therapy, 2013 [PDF]

, 2014
Multiple sclerosis (MS) is the most common chronic disease of the central nervous system in young adults. No curative therapy is known. Currently, six drugs are available that can reduce the activity of MS.
Bencsik, Krisztina, Karácsony, M., Vécsei, László   +2 more
core  

Investigation of fingolimod-induced lymphocyte sequestration on inflammatory response and neurological damages after cardiac arrest

Intensive Care Medicine Experimental
Background A sepsis-like syndrome is known to occur after cardiac arrest, leading to cerebral infiltration by white blood cells (WBC). We hypothesized that pharmacological sequestration of WBC, and more specifically lymphocytes within lymphoid tissues ...
Yara Abi Zeid Daou, Fanny Lidouren, Antoine Bois, Naoto Watanabe, Ali Jendoubi, Estelle Faucher, Mathieu Surenaud, Sophie Chateau-Joubert, Sophie Hue, Bijan Ghaleh, Matthias Kohlhauer, Renaud Tissier   +11 more
doaj   +1 more source

Is it time to target no evident disease activity (NEDA) in multiple sclerosis? [PDF]

, 2015
Banwell, Bermel, Cohen, Cohen, Coles, Coles, Comi, Confavreux, Dobson, Erbayat Altay, Giovannoni, Giovannoni, Giovannoni, Hartung, Havrdova, Kappos, Leray, Levesque, Miller, Rio, Scalfari, Solomon, Sormani, Sormani, Tuohy, Zivadinov   +25 more
core   +1 more source

Fingolimod for multiple sclerosis and emerging indications: appropriate patient selection, safety precautions, and special considerations

Therapeutics and Clinical Risk Management, 2016
Ilya Ayzenberg, Robert Hoepner, Ingo Kleiter Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany Abstract: Fingolimod (FTY720), an immunotherapeutic drug targeting the sphingosine-1-phosphate receptor, is a widely used ...
Ayzenberg I, Hoepner R, Kleiter I
doaj  

Protective role of fingolimod (FTY720) in rats subjected to subarachnoid hemorrhage [PDF]

, 2015
Chanannait Paisansathan, Dale A Pelligrino, Fernando D Testai, Hao-Liang Xu   +3 more
core   +1 more source

Therapeutic Potential of Fingolimod and Dimethyl Fumarate in Preclinical Pancreatic Cancer Models. [PDF]

Oncol Res
Gousseau P, Genest L, Froget G, Rupp T.
europepmc   +1 more source