Results 101 to 110 of about 17,802 (177)

Necrotizing fungal osteomyelitis and fingolimod, 4 years after treatment with fingolimod

, 2020
Fingolimod has been the first approved oral medication in MS for its relapsing remitting type. It is a non-selective sphingosine1-phosphate (S1P) receptor modulator on lymphocytes. Engagement of this receptor blocks the T cells and B cells migration from
Harirchian, M.H., Sadeghipour, A., Poursadeghfard, M., Kamali, H., Sarraf, P.   +4 more
core  

Effects of Crocin on Brain Neurotrophins, Cognition, Balance and Pain in Toxic-Induced Demyelination Model

Acta Neurologica Taiwanica
Objective: The purpose of this study was to investigate the effects of Crocin on brain neuroterophins, cognition, sensory and motor dysfunction and compare to fingolimod effects in toxic-induced demyelination with Ethidium Bromide (EB) in female Wistar ...
Rouholah Fatemi, Hadi Fathi Moghaddam, Yaghoub Farbod, Roya Bigtashkhani   +3 more
doaj   +1 more source

Clinical and radiological implications of subpotent generic fingolimod in multiple sclerosis: a case series

Therapeutic Advances in Neurological Disorders
An expansion in the availability of generic specialty disease modifying therapies (DMTs) for treatment of multiple sclerosis (MS) has increased recently.
Darin T. Okuda, Lauren M. Tardo, Crystal M. Wright, Shanan B. Munoz, Tom G. Punnen, Mahi A. Patel, Tatum M. Moog, Katy W. Burgess   +7 more
doaj   +1 more source

Therapeutic Potential of Fingolimod in Diabetes Mellitus and Its Chronic Complications

Jie Li,1,2 Xinyu Nan,1 Yixuan Ma,3 Zhen Wang,4 Hui Fang1,2 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, 050000, People’s Republic of China; 2Department of Endocrinology, Tangshan Gongren Hospital, Tangshan, 063000, People’s ...
Fang H, Li J, Ma Y, Nan X, Wang Z
core  

Investigation of fingolimod-induced lymphocyte sequestration on inflammatory response and neurological damages after cardiac arrest

Intensive Care Medicine Experimental
Background A sepsis-like syndrome is known to occur after cardiac arrest, leading to cerebral infiltration by white blood cells (WBC). We hypothesized that pharmacological sequestration of WBC, and more specifically lymphocytes within lymphoid tissues ...
Yara Abi Zeid Daou, Fanny Lidouren, Antoine Bois, Naoto Watanabe, Ali Jendoubi, Estelle Faucher, Mathieu Surenaud, Sophie Chateau-Joubert, Sophie Hue, Bijan Ghaleh, Matthias Kohlhauer, Renaud Tissier   +11 more
doaj   +1 more source

Three cases of non-carryover fingolimod-PML

, 2019
\(\bf Objective\) To report the course of 3 recent Japanese and European cases of fingolimod-associated progressive multifocal leukoencephalopathy (PML) and to analyze its risk factors and increased incidence in Japan.
Nakahara, Jin (PhD), Kamada, Masaki (PhD), Ayzenberg, Ilya (Prof. Dr. med.), Kufukihara, Kenji (MD), Takata, Tadayuki (MD), Tomaske, Laura, Schneider, Ruth (Dr. med.), Kume, Kodai (PhD), Deguchi, Kazushi (PhD), Gold, Ralf (Prof. Dr. med.)   +9 more
core   +1 more source

Phosphoproteomic dysregulation promotes tumor proliferation in Cushing's disease. [PDF]

Proc Natl Acad Sci U S A
Asuzu DT, Bhatt D, Mullaney D, Mandal D, Nwokoye D, Varghese S, Tortoza Lopez D, Ramavenkat N, Johnson K, Elkahloun AG, Abdullaev Z, Aldape K, Maric D, Quignon C, Malik N, Steiner JP, Li Y, Wray S, Tatsi C, Nieman LK, Chittiboina P.   +20 more
europepmc   +1 more source

Combined Modulation of Ceramide and S1P Pathways Induces Strong Cytotoxicity in SH-SY5Y Neuroblastoma Cells. [PDF]

Int J Mol Sci
Cakir CO, Sezer CV, Cengiz M, Kutlu HM.
europepmc   +1 more source

Fungal Infections Associated with Sphingosine 1-Phosphate Receptor Modulators: Immunological Mechanisms, Clinical Patterns, and Management Considerations. [PDF]

Microorganisms
Yazdan KM, Madam ST, Pasula S.
europepmc   +1 more source

Association of HALP score with clinical and radiological activity following fingolimod discontinuation in patients with multiple sclerosis. [PDF]

eNeurologicalSci
Gokce SF, Bolayir A, Demir E, Cigdem B.
europepmc   +1 more source