Results 31 to 40 of about 90,429 (267)
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Using sunflower seed husks waste for sustainable thermal isolating coatings [PDF]
The paper presents experimental results of the research carried out in order to obtain an innovative finishing/protection product for plasterboard surfaces, using sunflower seed husks, waste generated by the edible oils industry.
Irina POPA +3 more
doaj
CULLED BUFFALO HEIFERS AS A POTENTIAL SOURCE FOR BEEF PRODUCTION [PDF]
Culled buffalo heifers as a potential source for meat production was investigated in this research. Eighteen culled buffalo heifers were divided into three similar groups according to their initial age and body weight (37 month and 385 kg) allotted to
laila Eid, Safaa Khalil,
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Glimpse into reports on abrasive machining (Group G) during CIRP 2024 General Assembly
To promote the international cutting-edge technical exchange in the field of abrasives, the Group G (abrasive processing) papers in the 2024 CIRP Annals – Manufacturing Technology journal have been specially selected for introduction. A total of 9 papers
Jiang GUO, Rongyan SUN, Zili ZHANG
doaj +3 more sources
Environmental and industrial safety regulations have increased the possibilities of utilizing enzymes in textile processing to produce environmentally friendly output.
Menna M. Ragab +2 more
doaj +1 more source

