Results 31 to 40 of about 199,278 (289)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2021 Based on an analysis of the competitiveness of the European surface finishing industry, challenges are discussed and future directions for remaining competitive are recommended.
Hansal, W., +6 more
core +1 more source
Rock Hill Printing and Finishing Company Videos - Accession 1587 [PDF]
, 2018 This collection consists of two digital video files created by the Rock Hill Printing and Finishing Company to show to clients and explain the printing and finishing process and capabilities of the plant to their prospective clients. These professionally
Bleachery +1 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Scientific ReportsThe study examined the use of cationic polymers (Polyethyleneimine and chitosan) in treating fabrics like cotton, wool, and cotton/wool (70/30) to improve their dyeability and printability.
Eman M. Reda +3 more
doaj +1 more source
Flexible Abrasive Tools for the Deburring and Finishing of Holes in Superalloys
Journal of Manufacturing and Materials Processing, 2018 Many manufacturing sectors require high surface finishing. After machining operations such as milling or drilling, undesirable burrs or insufficient edge finishing may be generated.
Adrián Rodríguez +3 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Using sunflower seed husks waste for sustainable thermal isolating coatings [PDF]
Constructii: Journal of Civil Engineering Research, 2020 The paper presents experimental results of the research carried out in order to obtain an innovative finishing/protection product for plasterboard surfaces, using sunflower seed husks, waste generated by the edible oils industry.
Irina POPA +3 more
doaj