Results 51 to 60 of about 90,091 (268)
The artistic heritage of any nation is one of the most important factors that work for the establishment, continuation and survival of civilization throughout the ages, and applied arts are among the most important sources of reference materials ...
Mohammed Afify
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Assessing Intestinal Health in Pigs: Recognizing Unaddressed Areas and Prospective Research Avenues
Gut health is crucial for pigs because it affects nutrient absorption, immune function, and growth performance. However, its definition remains unclear, particularly regarding measurable responses in scientific studies.
Marina Patricia Walter +6 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Glimpse into reports on abrasive machining (Group G) during CIRP 2024 General Assembly
To promote the international cutting-edge technical exchange in the field of abrasives, the Group G (abrasive processing) papers in the 2024 CIRP Annals – Manufacturing Technology journal have been specially selected for introduction. A total of 9 papers
Jiang GUO, Rongyan SUN, Zili ZHANG
doaj +1 more source
Objetivou-se com este trabalho estimar as exigências nutricionais de energia líquida e metabolizável de animais Nelore, Nelore-Angus e Nelore-Simental, as eficiências de uso da energia metabolizável para ganho e mantença e a eficiência de deposição de ...
M.I. Marcondes +6 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
MODELS OF OIL WOOD COATING MATERIALS SELECTION ACCORDING TO TECHNOLOGICAL, OPERATIONAL, ECOLOGICAL AND ECONOMIC CRITERIA [PDF]
This article presents the use of system analysis methodology and Graph Theory for validation of the relationships among descriptive factors, which impact the selection of oil materials for wood finishing. Matrix analysis was used to determine the results
Larysa YAREMCHUK +3 more
doaj
Forty ewes (31.725±1.44 kg initial LW) were used to evaluate the effects of clinoptilolite (ZEOL) supplementation (0, 1, 2, and 3%, DM basis of diet) as substitute of soybean meal (SBM) in a finishing corn-based diet on growth performance, dietary ...
Alfredo Estrada-Angulo +8 more
doaj +1 more source

