Results 41 to 50 of about 614,247 (264)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Analysis of quasi-lattice distributions of statistics from finite population

Lietuvos Matematikos Rinkinys, 2004
Edgeworth expansions are used for approximation of quantiles, estimation of parameters, construction of confidence intervals and testing hypothesis. Paper shows how to construct  ` `  long'' Edgewort asymptotic expansions.
Jurgita Turkuvienė, Algimantas Bikelis
doaj   +3 more sources

Modified Estimator of Finite Population Variance under Stratified Random Sampling

Engineering Proceedings, 2023
This paper proposes a generalized estimator of finite population variance using the auxiliary information under stratified random sampling. The expressions for bias and mean square error equations of the proposed estimator up to the first degree of ...
Yahaya Zakari, Isah Muhammad
doaj   +1 more source

Number of adaptive steps to a local fitness peak

, 2011
We consider a population of genotype sequences evolving on a rugged fitness landscape with many local fitness peaks. The population walks uphill until it encounters a local fitness maximum.
Gillespie J. H., Jain K., Jain K. Seetharaman S., K. Jain, Orr H. A., Orr H. A., Sire C., Sornette D.   +7 more
core   +1 more source

Strategies for the evolution of sex [PDF]

, 2001
We find that the hypothesis made by Jan, Stauffer and Moseley [Theory in Biosc., 119, 166 (2000)] for the evolution of sex, namely a strategy devised to escape extinction due to too many deleterious mutations, is sufficient but not necessary for the ...
A. Bernardes, A. Kondrashov, A. Pekalski, Ayşe Erzan, B. Chopard, B. Drossel, B. Örcal, C. Chisholm, D. Stauffer, D. Stauffer, E.J. Lyons, E.P. Solomon, Erkan Tüzel, H.L. Muller, J. Maynard Smith, J. Maynard Smith, J. Maynard Smith, J. Thoms, J.M. Smith, J.S. SaMartins, L.M. Prescott, M. Eigen, N. Jan, R.J. Redfield, S.S. Mader, T.J. Penna, Volkan Sevim, W.D. Hamilton, Y. Cui   +28 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The time to extinction for an SIS-household-epidemic model

, 2009
We analyse a stochastic SIS epidemic amongst a finite population partitioned into households. Since the population is finite, the epidemic will eventually go extinct, i.e., have no more infectives in the population.
A Shwartz, C Bezuidenhout, C Doering, D Griffeath, F Arrigoni, F Ball, G Ghoshal, H Andersson, H Andersson, H Andersson, I Nåsell, J Wallinga, M Lindholm, NM Ferguson, P Neal, P Neal, Peter Neal, R Anderson, R Kryscio, S Cauchemez, S Ethier, T Hagenaars, T Harris, T House, T Liggett, Tom Britton   +25 more
core   +1 more source

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

On the Convergence of Population Protocols When Population Goes to Infinity

, 2009
Population protocols have been introduced as a model of sensor networks consisting of very limited mobile agents with no control over their own movement.
Bournez, Olivier, Chassaing, Philippe, Cohen, Johanne, Gerin, Lucas, Koegler, Xavier   +4 more
core   +3 more sources

Stochastic differential equations for evolutionary dynamics with demographic noise and mutations [PDF]

, 2012
We present a general framework to describe the evolutionary dynamics of an arbitrary number of types in finite populations based on stochastic differential equations (SDE).
Arne Traulsen, C. W. Gardiner, Christoph Hauert, F. A. C. C. Chalub, J. Hofbauer, J. Maynard Smith, J. W. Demmel, Jens Christian Claussen, M. A. Nowak, W. H. Sandholm, W. J. Ewens   +10 more
core   +2 more sources