Results 61 to 70 of about 65,109 (285)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Periodic complex map germs and foliations
Anais da Academia Brasileira de CiênciasIn this paper we study topological and analytical conditions on the orbits of a germ of diffeomorphism in the complex plane in order to obtain periodicity.
LEONARDO M. CÂMARA, BRUNO A. SCÁRDUA
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
CONTACTLESS MEASUREMENT OF KEY PARAMETERS OF LIMB VESSELS ON AN OCCLUSAL PLETHYSMOGRAPHY METHOD
Бюллетень сибирской медицины, 2013 The purpose of this publication – to familiarize the readers with the newest achievements in the field of vision machine technologies with regard to the occlusal plethysmography.
V. I. Kuznetsov +2 more
doaj +1 more source
Finiteness Conditions for Strictness Analysis
DAIMI Report Series, 1993 We give upper bounds on the number of times the fixed point operator needs to be unfolded for strictness analysis of functional languages with lists. This extends previous work both in the syntax-directed nature of the approach and in the ability to deal with Wadler's method for analysing lists. Limitations of the method are indicated.
Flemming Nielson, Hanne Riis Nielson
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Journal of High Energy Physics, 2023 The asymptotic symmetries of electromagnetism in all higher spacetime dimensions d > 4 are extended, by incorporating consistently angle-dependent u(1) gauge transformations with a linear growth in the radial coordinate at spatial infinity. Finiteness of
Oscar Fuentealba
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
European Physical Journal C: Particles and Fields, 2022 We address an interesting question in the present paper that whether the acoustic gravity can be applied as a tool to the study of regular black holes.
Chen Lan, Yan-Gang Miao, Yi-Xiong Zang
doaj +1 more source