Determination of Fipronil and Its Metabolites in Tea by Gas Chromatography-Negative Ion Chemical Ionization-Mass Spectrometry [PDF]
In this paper, a gas chromatography-negative ion chemical ionization-mass spectrometry (GC-NICI-MS) method was established for the determination of fipronil and its metabolites fipronil sulfone and fipronil sulfoxide in tea.
MA Yiying, HAO Yu, ZHANG Peng, LIU Mengmeng, YU Yang, SUN Xinyao, YU Litao
doaj +1 more source
CYP450-Dependent Biotransformation of the Insecticide Fipronil into Fipronil Sulfone Can Mediate Fipronil-Induced Thyroid Disruption in Rats [PDF]
In rats, the widely used insecticide fipronil increases the clearance of thyroxine (T(4)). This effect is associated with a high plasma concentration of fipronil sulfone, the fipronil main metabolite in several species including rats and humans. In sheep, following fipronil treatment, fipronil sulfone plasma concentration and thyroid disruption are ...
Béatrice B, Roques +8 more
openaire +4 more sources
Toxic effects of fipronil and its metabolites on PC12 cell metabolism
Fipronil and its metabolites (fipronil sulfone, fipronil sulfide and fipronil desulfinyl) adversely affect the environment and human health. Targeted metabolomics and lipidomics based on ultra-performance liquid chromatography-tandem mass spectrometry ...
Xiao Song +5 more
doaj +1 more source
An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 1: new molecules, metabolism, fate, and transport [PDF]
With the exponential number of published data on neonicotinoids and fipronil during the last decade, an updated review of literature has been conducted in three parts.
Bonmatin, Jean-marc +7 more
core +3 more sources
Accumulation and biotransformation of pesticides in fish tissues are essential to assess their toxicity and associated human exposure risk. The mechanisms on time-dependent and tissue-specific accumulation and transformation of fipronil in adult fish are
Jing-Xin Wang +3 more
doaj +1 more source
Fipronil and fipronil sulfone in chicken: From in vitro experiments to in vivo PBK model predictions
In 2017 a large-scale fipronil contamination in eggs occurred in several European countries. Fipronil and its metabolites have the potential to be transferred into the eggs of laying hens, thereby entering the human food chain. Here, first the metabolism of fipronil was measured in vitro using chicken liver S9.
Lautz, L.S. +4 more
openaire +3 more sources
Fipronil -a broad spectrum phenylpyrazole insecticide has high level of toxicity towards environment. Therefore, an easy and reliable analytical method was developed for residue estimation of fipronil to ensure food and environmental safety.
Ayan Mukherjee +5 more
doaj +1 more source
Bench‐Stable Electrophilic Reagents for the Direct Di‐ and Trifluoroethylthiolation of Indoles
Abstract Two saccharine‐based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large‐scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open‐flask reactions.
Paula Casasús +4 more
wiley +1 more source
The occurrence of pesticides and their metabolites in the environment can alter the ecological relationships between aquatic food chains. Fipronil is a broad-spectrum insecticide which release in the environment may harm the non-target organisms. However,
Yingjuan Ou +5 more
doaj +1 more source
Multibiomarker responses and bioaccumulation of fipronil in Prochilodus lineatus exposed to spiked sediments: Oxidative stress and antioxidant defenses [PDF]
Fipronil is a current use pesticide, widely used in many crops, commonly adsorbed to sediments of aquatic environments. The purpose of this study was to evaluate the biomarker responses and fipronil distribution pattern in different matrixes (fish ...
de la Torre, Fernando Roman +3 more
core +1 more source

