Results 81 to 90 of about 1,110 (181)

Induction of Amyloid-beta(42) Production by Fipronil and Other Pyrazole Insecticides [PDF]

, 2018
Generation of amyloid-β peptides (Aβs) by proteolytic cleavage of the amyloid-β protein precursor (AβPP), especially increased production of Aβ42/Aβ43 over Aβ40, and their aggregation as oligomers and plaques, represent a characteristic feature of ...
Auvray, P, Barnych, B, Blennow, K, Bodin, M, Bohl, B, Cam, M, Durieu, E, Fraering, J, Fraering, PC, Garbis, SD, Gerber, H, Gizzi, P, Haber, VE, Hammock, BD, Hata, S, Karg, F, Koch, P, Koslowski, S, Manousopoulou, A, Meijer, L, Mihaljevic, B, Omori, C, Pannee, J, Portelius, E, Suzuki, T, Tavcar, B, Vasylieva, N, Yamamoto, K, Zetterberg, H   +28 more
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Fipronil Promotes Adipogenesis via AMPKα-mediated Pathway in 3T3-L1 Adipocytes [PDF]

, 2016
Emerging evidence suggests that organochlorine, organophosphorus and neonicotinoid insecticide exposure may be linked to the development of obesity and type 2 diabetes.
Clark, John M, Park, Yeonhwa, Sun, Quancai, Yang, Jeremy, Yoon, Kyong-Sup   +4 more
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Little and often makes much: identifying the time-reinforced toxicity of pesticides and their impacts on bees [PDF]

, 2016
Bees provide important pollination services for crops and wild flowers, estimated to be valued at £120 billion to the global economy. However, declining bee populations have put these services in jeopardy.
Holder, Philippa Jane
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Les perturbateurs endocriniens :enjeux pour le consommateur et défis scientifiques

, 2012
Les perturbateurs endocriniens potentiellement associés à des problèmes de santé publique présentent une multitude d’enjeux sociétaux, législatifs et sanitaires. Actuellement aucune définition officiellement validée ne précise la nature de ces substances
Gayrard-Troy, Véronique,, Picard-Hagen, Nicole, Viguié, Catherine   +2 more
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A Quantitative Structure Activity Relationship for acute oral toxicity of pesticides on rats: Validation, Domain of Application and Prediction

, 2016
International audienceQuantitative Structure Activity Relationship (QSAR) models are expected to play an important role in the risk assessment of chemicals on humans and the environment. In this study, we developed a validated QSAR model to predict acute
Amrane, Abdeltif, Benkortbi, Othmane, Hamadache, Mabrouk, Hanini, Salah, Khaouane, Latifa, Si Moussa, Cherif   +5 more
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CYP450-Dependent Biotransformation of the Insecticide Fipronil into Fipronil Sulfone Can Mediate Fipronil-Induced Thyroid Disruption in Rats (Full paper and erratum)

, 2012
In rats, the widely used insecticide fipronil increases the clearance of thyroxine (T-4). This effect is associated with a high plasma concentration of fipronil sulfone, the fipronil main metabolite in several species including rats and humans. In sheep, following fipronil treatment, fipronil sulfone plasma concentration and thyroid disruption are ...
ROQUES, Beatrice, Lacroix, Marlène, Puel, Sylvie, Gayrard, Véronique, Picard-Hagen, Nicole, Jouanin, Isabelle, Perdu, Elisabeth, Martin , Pascal   +7 more
openaire   +1 more source

Environ Int [PDF]

Occupational medical surveillance is highly desirable in manufacturing facilities where exposure to chemicals is significant. The insecticide fipronil is generally considered safe for humans but with increasing use, exposure to fipronil is of concern ...

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Hydrophobic Organic Contaminants in Urban-Impacted Coastal Marine Sediments [PDF]

, 2019
Hydrophobic organic contaminants (HOCs) are anthropogenic compounds that have been used for many decades in a wide range of applications. Due to human activities and improper disposal, many HOCs have been deposited into aquatic environments where they ...
Taylor, Allison Reine
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Toxicologie comparative du fipronil et de son principal métabolite le fipronil sulfone: complémentarité des modèles animaux et cellulaires

, 2011
Un modèle de mesure de la clairance de la T4 à partir de culture d'hépatocytes a été développé afin de préciser le potentiel perturbateur thyroïdien relatif du fipronil et du fipronil sulfone par des approches de type data-réponse.
Roques, Béatrice, Lacroix, Marlène Z., Puel, Sylvie, Kesteman, Anne-Sylvie, Jouanin, Isabelle, Perdu, Elisabeth, de Sousa, Georges, Rahmani, Roger, Gayrard-Troy, Véronique, Picard-Hagen, Nicole, Viguié, Catherine   +10 more
openaire   +2 more sources

Le fipronil, agent de perturbation thyroïdienne ? : exposition et réévaluation de sa toxicité dans l'espèce ovine, modèle pour la régulation thyroïdienne de l'Homme [PDF]

, 2009
Si le fipronil est reconnu comme pertubateur thyroïdien et inducteur de tumeurs de la thyroïde chez le rat, sa toxicité thyroïdienne envers l'Homme reste inconnue. Ce travail consiste à étudier l'impact du fipronil dans l'espèce ovine, sur des animaux de
Pelissié, Elodie
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