Results 161 to 170 of about 2,636 (176)

Sequence analysis of the 3′ end of the feline coronavirus FIPV 79-1146 genome: Comparison with the genome of porcine coronavirus TGEV reveals large insertions [PDF]

open access: yesVirology, 1988
The genetic information, carried on mRNA 6 of feline infectious peritonitis virus (FIPV) strain 79-1146, was determined by sequence analysis of cDNA clones derived from the 3' end of the FIPV genome. Two ORFs were found, encoding polypeptides of 11K (ORF-1) and 22K (ORF-2).
Raoul J De Groot   +2 more
exaly   +4 more sources

Antigenic analysis of feline coronaviruses with monoclonal antibodies (MAbs): Preparation of MAbs which discriminate between FIPV strain 79-1146 and FECV strain 79-1683

open access: yesVeterinary Microbiology, 1991
We prepared 31 monoclonal antibodies (MAbs) against either FIPV strain 79-1146 or FECV strain 79-1683, and tested them for reactivity with various coronaviruses by indirect fluorescent antibody assay (IFA). Sixteen MAbs which reacted with all of the 11 strains of feline coronaviruses, also reacted with canine coronavirus (CCV) and transmissible ...
T Hohdatsu, Hidekazu Koyama
exaly   +3 more sources

Porcine epidemic diarrhea virus (CV 777) and feline infectious peritonitis virus (FIPV) are antigenically related [PDF]

open access: yesArchives of Virology, 1988
Using gut sections from pigs infected with porcine epidemic diarrhea virus (strain CV 777) and ascitic fluid from cats which had succumbed to feline infectious peritonitis (FIP), a weak cross reaction was found by immunofluorescence. Its specificity was confirmed when detergent-treated purified CV 777 showed a prominent reaction with FIPV antibodies in
Horzinek, M.C.   +4 more
exaly   +4 more sources

Single-site mutation (M1058L) of feline infectious peritonitis virus (FIPV) spike protein in domestic cats of Northern Vietnam

Archives of Virology
Feline coronavirus (FCoV) has two biotypes: feline enteric coronavirus (FECV), which typically causes mild intestinal infections, and feline infectious peritonitis virus (FIPV), a virulent form associated with a fatal systemic and infectious disease in cats, known as feline infectious peritonitis (FIP).
Quang Hong Duong   +2 more
exaly   +3 more sources

Antibody-based Therapeutic Drug Development of Feline Infectious Peritonitis (FIPV) 2866

The Journal of Immunology
Abstract Description   Feline infectious peritonitis (FIP) is a fatal progressive viral disease, and no effective therapy and safe vaccine are available due to antibody-dependent enhancement (ADE).
Yi Wen Shen, Yen Chen Chang
openaire   +1 more source

Design of novel chiral self-assembling peptides to explore the efficiency and mechanism of mRNA-FIPV vaccine delivery vehicles

International Journal of Pharmaceutics
The enhancement of conventional liposome and lipid nanoparticle (LNP) methodologies in the formulation and deployment of messenger RNA (mRNA) vaccines necessitates further refinement to augment both their effectiveness and biosafety profiles. Additionally, researching these innovative delivery carrier materials represents both a prominent focus and a ...
Na, Lu   +12 more
openaire   +2 more sources

Identification of novel broad-spectrum antiviral drugs targeting the N-terminal domain of the FIPV nucleocapsid protein

International Journal of Biological Macromolecules
Coronaviruses pose serious threats to human and animal health worldwide, of which their structural nucleocapsid (N) proteins play multiple key roles in viral replication. However, the structures of animal coronavirus N proteins are poorly understood, posing challenges for research on their functions and pathogenic mechanisms as well as the development ...
Jintao, Zhang   +11 more
exaly   +3 more sources

Dynamic shifts in gut microbiota composition of cats following oral infection with the virulent FIPV strain rQS-79 and treatment with GS-441524

Veterinary Microbiology
Feline infectious peritonitis (FIP) is a fatal disease caused by a mutant strain of feline coronavirus (FCoV), and its progression is closely related to gut microbiota and immune response. This study aimed to investigate the changes in the fecal microbiota composition of cats experimentally infected with FIPV, with and without antiviral treatment ...
Ashenafi Assefa, Gebremariam   +5 more
openaire   +2 more sources

Assessing urban morphology's impact on solar potential of high-rise facades in Hong Kong using machine learning: An application for FIPV optimization

Sustainable Cities and Society
The relationship between solar potential on building façade and urban morphology at urban scale remains unclear, and the design of façade integrated photovoltaic (FIPV) lacks evidence. This study investigates high-rise, high-density commercial districts in Hong Kong (HK), using Random Forest algorithm combined with the SHapley Additive exPlanations ...
Lulu Tao, Mengmeng Wang, Changying Xiang
openaire   +2 more sources

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