Results 41 to 50 of about 900,751 (332)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Comparison between Mullite-Based and Anorthite-Based Porcelain Tiles: A Review

Eng, 2023
This paper begins with an introduction to porcelain tiles. A review of the major scientific and technological features of mullite-based porcelain tiles (MPTs) and anorthite-based porcelain tiles (APTs), focusing primarily on the raw material, processing,
Kun Li, Eloise de Sousa Cordeiro, Agenor De Noni   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

“When I Sleep Poorly, It Impacts Everything”: An Exploratory Qualitative Investigation of Stress and Sleep in Junior Endurance Athletes

Frontiers in Psychology, 2021
On their journeys toward senior athletic status, junior endurance athletes are faced with a multitude of stressors. How athletes react to stressors plays a vital part in effective adaptation to the demanding, ever-changing athletic environment.
Maria Hrozanova, Kristian Firing, Frode Moen   +2 more
doaj   +1 more source

Approximate, not perfect synchrony maximizes the downstream effectiveness of excitatory neuronal ensembles [PDF]

, 2014
The most basic functional role commonly ascribed to synchrony in the brain is that of amplifying excitatory neuronal signals. The reasoning is straightforward: When positive charge is injected into a leaky target neuron over a time window of positive ...
Börgers, Christoph, Kopell, Nancy, Li, Jie   +2 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Population rate codes carried by mean, fluctuation and synchrony of neuronal firings

, 2008
A population of firing neurons is expected to carry information not only by mean firing rate but also by fluctuation and synchrony among neurons. In order to examine this possibility, we have studied responses of neuronal ensembles to three kinds of ...
Amit, Anderson, Arsiero, Aviel, Brunel, Brunel, Burkitt, Burkitt, Burkitt, Chance, Chapin, de Oliveira, deCharms, Doiron, Eggert, Ermentrout, Fox, Fries, Grammont, Greiner, Haken, Hasegawa, Hasegawa, Hasegawa, Hasegawa, Hasegawa, Hasegawa, Hasegawa, Hasegawa, Haskell, Heinzle, Hideo Hasegawa, Hopfield, Hyvärinen, Ibanes, Knight, Kuhn, Lindner, Lindner, Lindner, Longtin, Masuda, Moreno, Oizumi, Omurtag, Renart, Reyes, Richardson, Riehle, Rieke, Rodriguez, Rudlph, Rümelin, Salinas, Salinas, Schindler, Shadlen, Shriki, Silberberg, Tiesinga, Tiesinga, Ursey, Wang, Wilson   +63 more
core   +1 more source

Checkpoint-Dependent Regulation of Origin Firing and Replication Fork Movement in Response to DNA Damage in Fission Yeast [PDF]

, 2009
To elucidate the checkpoint mechanism responsible for slowing passage through S phase when fission yeast cells are treated with the DNA-damaging agent methyl methanesulfonate (MMS), we carried out two-dimensional gel analyses of replication intermediates
Huberman, Joel A., Kumar, Sanjay
core   +3 more sources

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Indicaciones neuroquirúrgicas en el C.B.P.

Cirugía del Uruguay, 1982
Los autores analizan la incidencia de las metástasis cerebrales únicas y múltiples en el CBP. Se subraya la importancia actual de la Tomografía Computada en su diagnóstico y el valor del método para las indicaciones terapéuticas.
Sasha Gordon-Firing, Carlos Garbino
doaj