Results 71 to 80 of about 176,812 (282)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Evaluation and Critical Sociological Analysis of the Representation of Feminine Identity in the Novels of Mohammad Hejazi [PDF]
فصلنامه نقد ادبی, 2023 While the quality of women's lives and their status and position can be indicative of the prominent cultural and civilizational features of a society, in most societies, especially in our patriarchal society, we witness a kind of liminality ...
, Arman hedari, ,
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Functional Fixation on the Valuation of the Firm [PDF]
مطالعات تجربی حسابداری مالی, 2006 Valuation theories and models have evolved over time from the very simple present value formulation to more complex relationships. But the causality between accounting numbers and the value of the firm has not been succinctly developed investors ...
Hamid khaleghi Moghadam +1 more
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Pilot 1 user-generated-content [PDF]
, 2019 The information of this dataset will be provided by the users who will participate in the Gallery visits, and will contribute content participating in the experiments using the CrossCult Pilot 1 app.
Padfield Joseph +3 more
core +1 more source
Examining Overreaction in Indian Stock Market for Quarterly News
Emerging Markets Journal, 2014 Market Overreaction is a very familiar and age-old craze amongst traders. Pigou (1929) defined it as a ‘conducting rod along which an error of optimism or pessimism, once generated, propagates itself about the business world.’ The question of whether or
Sitangshu Khatua, Hemant Kumar Pradhan
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source