Results 91 to 100 of about 1,434,413 (310)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Share holding Pattern and Firm Performance [PDF]

open access: yes
Corporate Governance deals with the issue of how suppliers of finance to corporations assure themselves of getting a return on their investment. Several Studies have examined the relationship between ownership structure and firm performance.
Jayesh Kumar
core  

Performance of debt free firms [PDF]

open access: yesManagerial Finance, 2009
PurposeThe purpose of this paper is to find out whether investors tend to reward firms that resist the urge to borrow and operated with debt free balance sheet and penalize firms that have high levels of debt.Design/methodology/approachThe performance of portfolios of debt free firms are compared to comparable portfolios of leveraged firms.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Who benefits from reducing the cost of formality? Quantile regression discontinuity analysis [PDF]

open access: yes, 2010
This paper studies the effects of increasing formality via tax reduction and simplification schemes on micro-firm performance. It uses the 1997 Brazilian SIMPLES program.
Gabrieli, Tommaso   +2 more
core   +1 more source

Partial Privatization and Firm Performance [PDF]

open access: yesSSRN Electronic Journal, 2003
ABSTRACTMost privatization programs begin with a period of partial privatization in which only non‐controlling shares of firms are sold on the stock market. Since management control is not transferred to private owners it is widely contended that partial privatization has little impact.
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Mediating effect of firm efficiency on the controlling shareholdings–firm performance nexus: evidence from public listed firms in Malaysia

open access: yesFinancial Innovation
This study examines how controlling shareholders influence firm performance through the mediating role of firm efficiency in transforming inputs into outputs.
Irene Wei Kiong Ting   +3 more
doaj   +1 more source

Human capabilities and firm performance in women-owned micro and small-medium enterprises: The mediating role of substantive and dynamic capabilities

open access: yesSmall Business International Review
Dynamic capabilities are widely recognized as a catalyst for firm performance yet there is a dearth of research on how dynamic capabilities work with human and substantive capabilities to contribute to firm performance particularly in women-owned micro ...
Antoinette Flynn   +2 more
doaj   +1 more source

Founding family firms, CEO incentive pay, and dual agency problems [PDF]

open access: yes, 2016
This paper contributes to the literature on agency theory by examining relations between family involvement and CEO compensation. Using a panel of 362 small U.S.
Mazur, Mieszko, Wu, Betty H.-T.
core   +3 more sources

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