Results 101 to 110 of about 96,219 (310)

Using Virtual Reality Social Environments to Promote Outcomes' Generalization of AVATAR Therapy for Distressing Voices: A Case Study

open access: yesJournal of Clinical Psychology, Volume 81, Issue 6, Page 516-525, June 2025.
ABSTRACT AVATAR therapy (AT) works by facilitating a ‘face‐to‐face’ dialog between the person and a digital representation (avatar) of their persecutory voice. Although there is cumulative evidence of this way of working with voices, enhancing the therapeutic focus on improved confidence and a sense of control of the voices in social situations ...
Mar Rus‐Calafell   +10 more
wiley   +1 more source

Alexithymia in Schizophrenia and Psychosis Vulnerability: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Psychology, Volume 81, Issue 6, Page 410-424, June 2025.
ABSTRACT Aims Disturbances involving impairments in experience and expression of affect are frequently identified in schizophrenia samples. Alexithymia underlies cognitive impairments in identification and expression of affect, further implicated in affect dysregulation.
Ercan Ozdemir   +3 more
wiley   +1 more source

Altered insular function during aberrant salience processing in relation to the severity of psychotic symptoms

open access: yesFrontiers in Psychiatry, 2016
There is strong evidence for abnormal salience processing in patients with psychotic experiences. In particular, there are indications that the degree of aberrant salience processing increases with the severity of positive symptoms.
Anna Walter   +10 more
doaj   +1 more source

A Holistic Wellness Prescription for Parkinson's Disease: Evidence‐Based Perspectives and Unmet Needs

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background In modern medicine the concept of wellness is often accompanied by various misconceptions arising from several factors, including a lack of clear definitions, the commercialization of wellness, and prevailing biases and stereotypes.
Indu Subramanian   +40 more
wiley   +1 more source

Metacognitive function and fragmentation in schizophrenia: Relationship to cognition, self-experience and developing treatments [PDF]

open access: yes, 2019
Bleuler suggested that fragmentation of thought, emotion and volition were the unifying feature of the disorders he termed schizophrenia. In this paper we review research seeking to measure some of the aspects of fragmentation related to the experience ...
Bonfils, Kelsey   +6 more
core   +2 more sources

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma   +14 more
wiley   +1 more source

Phosphorylation of transcription factor specificity protein 4 is increased in peripheral blood mononuclear cells of first-episode psychosis.

open access: yesPLoS ONE, 2015
BackgroundAltered expression of transcription factor specificity protein 4 (SP4) has been found in the postmortem brain of patients with psychiatric disorders including schizophrenia and bipolar disorder.
Raquel Pinacho   +7 more
doaj   +1 more source

Early Substance Use Cessation Improves Cognition—10 Years Outcome in First-Episode Psychosis Patients

open access: yesFrontiers in Psychiatry, 2019
Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates.
Melissa A. Weibell   +28 more
doaj   +1 more source

Bipolar Disorder as a Long‐Term Risk Factor for Parkinson's Disease: A Nationwide Case–Control Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Previous studies suggest an association between bipolar disorder (BD) and an increased risk of Parkinson's disease (PD), but the long‐term temporal relationship remains unclear. Particularly, it is unclear whether the risk of PD is influenced by the duration since BD diagnosis.
Elina Jaakkola   +5 more
wiley   +1 more source

Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia [PDF]

open access: yes, 2008
The frontal lobe has an extended maturation period and may be vulnerable to the long-term effects of schizophrenia. We tested this hypothesis by studying the relationship between duration of illness (DoI), grey matter (GM) and cerebro-spinal fluid (CSF ...
Abe   +67 more
core   +1 more source

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