Prevention of the First Episode of Psychosis [PDF]
Long a desired goal but increasingly a focus of research on clinical practice, prevention of psychosis has emerged as one of the most promising and effective areas of investigational interest and effort in psychiatry. Spurred by long-term studies that have associated outcome with duration of untreated psychosis, current research is focused on improving
openaire +2 more sources
Duration of untreated psychosis and social function: 1-year follow-up study of first-episode schizophrenia. [PDF]
BACKGROUND: In first-episode schizophrenia, longer duration of untreated psychosis (DUP) predicts poorer outcomes. AIMS: To address whether the relationship between DUP and outcome is a direct causal one or the result of association between symptoms and ...
Barnes, T. R. +17 more
core +1 more source
The Development of a Complex FEP Program at Semmelweis University
Introduction First episode psychosis (FEP) programs target the first 3-5 years after the first manifestation of a psychotic episode. Although follow-up results after 10-15 years are mixed, reported results of the first 5-10 years are promising in ...
V. Simon +5 more
doaj +1 more source
Mentalizing in first-episode psychosis
Mentalizing deficits have often been observed in people with schizophrenia and a few recent studies suggest that such deficits are also present in patients with first episode psychosis (FEP). It is not clear, however, whether these mentalizing deficits in FEP can be accounted for by underlying processes such as social cue recognition, social knowledge ...
Amélie M, Achim +3 more
openaire +3 more sources
Don’t turn your back on the symptoms of psychosis : a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK [PDF]
Background: Reducing the duration of untreated psychosis (DUP) is an aspiration of international guidelines for first episode psychosis; however, public health initiatives have met with mixed results.
Patterson, Paul +25 more
core +1 more source
Insular volume abnormalities associated with different transition probabilities to psychosis [PDF]
Background Although individuals vulnerable to psychosis show brain volumetric abnormalities, structural alterations underlying different probabilities for later transition are unknown.
McGuire, P. +42 more
core +1 more source
The Role of the Microbiome in First Episode of Psychosis
The relationship between the gut-brain-microbiome axis has gained great importance in the study of psychiatric disorders, as it may represent a new target for their treatment. To date, the available literature suggests that the microbiota may influence the pathophysiology of several diseases, including psychosis.
Lucero Nuncio-Mora +6 more
openaire +3 more sources
Predicting psychosis in at-risk patients using abnormal neural oscillations and synchrony in conjunctions with machine learning algorithms [PDF]
In the last 20 years, there has been a marked increase in interest in the early detection and treatment of psychosis. Despite the various potential “prodromes” that have been identified and have helped to increase the accuracy in the detection of persons
Ramyead, Avinash
core +1 more source
Treatment principles of first-episode psychosis
Treatment of first-episode psychosis, which has unique advantages and challenges, has an impact on the course of the illness. On one hand, clinician has to understand triggering factors of psychosis and make differential diagnosis, and on other hand he has to choose a rationale psychopharmacological treatment.
openaire +3 more sources
Brain structural and neurofunctional correlates of liability to psychosis : a multimodal neuroimaging approach [PDF]
Schizophrenia is one of the most debilitating and still not entirely understood mental diseases. Improvements in the treatment came hand in hand with an introduction of antipsychotics and thus with better understanding of neurobiology underlying its ...
Smieskova, Renata
core +1 more source

