Results 31 to 40 of about 13,418,784 (259)

Retrospective study on structural neuroimaging in first-episode psychosis [PDF]

PeerJ, 2016
Background. No consensus between guidelines exists regarding neuroimaging in first-episode psychosis. The purpose of this study is to assess anomalies found in structural neuroimaging exams (brain computed tomography (CT) and magnetic resonance imaging ...
Ricardo Coentre, Amilcar Silva-dos-Santos, Miguel Cotrim Talina   +2 more
doaj   +2 more sources

Timing of antipsychotics and benzodiazepine initiation during a first episode of psychosis impacts clinical outcomes: Electronic health record cohort study

Frontiers in Psychiatry, 2022
The impact of timing of antipsychotics and benzodiazepine treatment during a first episode of psychosis on clinical outcomes is unknown. We present a RECORD-compliant electronic health record cohort study including patients (n = 4,483, aged 14–35) with a
Maite Arribas, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Trevor Thompson, Dominic Oliver, Paolo Fusar-Poli, Paolo Fusar-Poli, Paolo Fusar-Poli, Paolo Fusar-Poli   +10 more
doaj   +1 more source

Ethnic variations in compulsory detention and hospital admission for psychosis across four UK Early Intervention Services [PDF]

, 2014
Substantial ethnic variations have been found in incidence, pathways to care and outcomes in psychosis. It is unknown whether these remain as marked in the presence of specialist Early Intervention Services (EIS) for psychosis.
Barnaby Major, Lawrence, J, Johnson, S, Joyce, John, Andrew Tapfumaneyi, Joyce, J, Fisher, Helen L; id_orcid, Jo Lawrence, Tapfumaneyi, A, Hinton, MF, Helen L Fisher, Lawrence, Jo, Hinton, Mark F, Sonia Johnson, John Joyce, Mark F Hinton, Johnson, Sonia, Fisher, HL, Mann, F, Farhana Mann, Major, Barnaby, Tapfumaneyi, Andrew, Major, B, Mann, Farhana   +23 more
core   +2 more sources

Modular Functional-Metabolic Coupling Alterations of Frontoparietal Network in Schizophrenia Patients

Frontiers in Neuroscience, 2019
Background: Brain functional dysconnectivity, as well as altered network organization, have been demonstrated to occur in schizophrenia. Brain networks are increasingly understood to exhibit modular community structures, which provides advantages in ...
Qiong Xiang, Jiale Xu, Jiale Xu, Yingchan Wang, Tianyi Chen, Jinhong Wang, Kaiming Zhuo, Xiaoyun Guo, Kristina Zeljic, Kristina Zeljic, Wenli Li, Wenli Li, Yu Sun, Zheng Wang, Yao Li, Yao Li, Dengtang Liu, Dengtang Liu   +17 more
doaj   +1 more source

Proxy measures for the assessment of psychotic and affective symptoms in studies using electronic health records

BJPsych Open
Background There is a lack of standardised psychometric data in electronic health record (EHR)-based research. Proxy measures of symptom severity based on patients' clinical records may be useful surrogates in mental health EHR research. Aims This study
Álvaro López-Díaz, Fernanda Jazmín Palermo-Zeballos, Luis Gutierrez-Rojas, Luis Alameda, Francisco Gotor-Sánchez-Luengo, Nathalia Garrido-Torres, Johann Métrailler, Livia Alerci, Vincent Bonnarel, Pablo Cano-Domínguez, Elma Avanesi-Molina, Miguel Soto-Ontoso, Rocio Torrecilla-Olavarrieta, Leticia Irene Muñoz-Manchado, Pedro Torres-Hernández, Fermín González-Higueras, Juan Luis Prados-Ojeda, Mario Herrera-Cortés, José Miguel Meca-García, Rafael Manuel Gordillo-Urbano, Cristina Sánchez-Robles, Tomás Delgado-Durán, María Felipa Soriano-Peña, Philippe Golay, Philippe Conus, Benedicto Crespo-Facorro, Miguel Ruiz-Veguilla   +26 more
doaj   +1 more source

A systematic review of PTSD to the experience of psychosis: prevalence and associated factors

BMC Psychiatry, 2021
Background Psychosis can be a sufficiently traumatic event to lead to post-traumatic stress disorder (PTSD). Previous research has focussed on the trauma of first episode psychosis (FEP) and the only review to date of PTSD beyond the first episode period
Georgina Buswell, Zoë Haime, Brynmor Lloyd-Evans, Jo Billings   +3 more
doaj   +1 more source

Neurocognitive functioning and emotional recognition in first-episode psychosis: protocol for a follow- up study

European Psychiatry
Introduction Although deficits in neurocognitive functioning and emotional recognition impact treatment outcomes in schizophrenia since the development of the first psychotic episode (FEP), there is still a lack of longer follow-up studies showing the ...
D. Bošnjak Kuharić, P. Makaric, K. Brozic, L. Tomasic, A. Savic, D. Ostojic, M. Rojnic Kuzman   +6 more
doaj   +1 more source

First episode psychosis related to COVID-19 infection

European Psychiatry, 2022
Introduction During the course of COVID-19 pandemic, The respiratory system is the most commonly affected while many neuropsychiatric manifestations of the disease have been observed.
S. Dhakouani, R. Kammoun, M. Skini, M. Karoui, F. Ellouz   +4 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Design of the BiRmingham Early Detection In untREated psyChosis Trial (REDIRECT): cluster randomised controlled trial of general practitioner education in detection of first episode psychosis [ISRCTN87898421]

BMC Health Services Research, 2005
Background Treatment delay in first episode psychosis is common. As general practitioners are the first point of contact for many individuals with first episode psychosis, they are well placed to detect the early symptoms and make urgent referrals to ...
Freemantle Nick, Birchwood Max, Lester Helen, Tait Lynda, Wilson Sue   +4 more
doaj   +1 more source