Results 41 to 50 of about 13,418,784 (259)

Dissociation of long-term verbal memory and fronto-executive impairment in first-episode psychosis [PDF]

, 2009
Background: Verbal memory is frequently and severely affected in schizophrenia and has been implicated as a mediator of poor clinical outcome. Whereas encoding deficits are well demonstrated, it is unclear whether retention is impaired.
Robbins, T. W., Barnes, T. R. E., T. R. E. Barnes, M. A. Ron, Franklin, C., T. W. Robbins, C. Franklin, E. M. Joyce, Ron, M. A., I. Harrison, Harrison, M., Joyce, E. M., Leeson, V. C., V. C. Leeson, M. Harrison, Harrison, I.   +15 more
core   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula, Juvy Rabelas, Kareem Touleimat, Elaine Marchi, Ruhi Shah, Shaydah Kheradmand, Kuldeep Singh, Karen Amble, Gholson J. Lyon   +8 more
wiley   +1 more source

Mindfulness, self-stigma and social functioning in first episode psychosis: a brief report [PDF]

, 2015
This study aimed to test the hypothesis that people with first-episode psychosis who are more mindful will have lower self-stigma, and hence better social functioning.
Mersh, L., Oliver, J., Jones, F.
core   +1 more source

Influence of Molecular Genetic Classes on Behavior in Prader‐Willi Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A wide range of behavioral phenotypes has been described in PWS patients including autism spectrum disorder (ASD). The prevalence of behavioral disorders was studied in 292 participants over 3 years with genetically confirmed PWS (N = 164 females and N = 128 males) with deletion (N = 182) and mUPD (maternal uniparental disomy) (N = 99).
Ranim Mahmoud, Merlin G. Butler, Wai Park, Jennifer L. Miller, Daniel J. Driscoll, June‐Anne Gold, Virginia Kimonis   +6 more
wiley   +1 more source

Clozapine prescribing during follow-up of a first-episode psychosis cohort

European Psychiatry, 2021
Introduction Of those with schizophrenia, one third develop treatment-resistant illness. Nearly 60% of these benefit from clozapine- the only antipsychotic medication licensed in this group.
R. Rowntree, F. Fanning, D. Keating, S. Murray, A. Szigeti, R. Doyle, S. Mcwilliams, M. Clarke   +7 more
doaj   +1 more source

Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi, Céline Louveau, Bertrand Diebold, Natacha Gaitch, Arnaud Hubas, Martine Gautier Vallee, Jérôme Champ, Anais L'Haridon, Sophie Georgin Lavialle, Boris Chaumette, Thierry Bienvenu   +10 more
wiley   +1 more source

Standardization of measurement and reporting of medication adherence using the TEN‐SPIDERS tool for claims data

British Journal of Clinical Pharmacology, EarlyView.
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori, Tzu‐Yung Kuo, Jenni Ilomäki, Monique F. Kilkenny, Stella Talic, Zanfina Ademi, J. Simon Bell, Jedidiah I. Morton, Lachlan L. Dalli   +8 more
wiley   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Prescribing in First Episode Psychosis

BJPsych Open
Aims This audit aimed to review prescribing in First Episode Psychosis (FEP) in Gloucestershire Health and Care NHS Trust, against NICE guidelines (CG 178) we hoped to develop prescribing guidelines for the Trust and to compare our results with Avon and
Edita Searle, Raeema Patel, Robertson Macpherson   +2 more
doaj   +1 more source

Neuroanatomical abnormalities that predate the onset of psychosis : a multicenter study [PDF]

, 2011
People experiencing possible prodromal symptoms of psychosis have a very high risk of developing the disorder, but it is not possible to predict, on the basis of their presenting clinical features, which individuals will subsequently become psychotic ...
James M. Stone, Wood, Stephen J., Pantelis, Christos, Borgwardt, Stefan J, James Woolley, Anita Riecher-Rössler, Eva M. Meisenzahl, Stone, James M, Tognin, Stefania, Isabel Valli, McGuire, Philip, Lisa J. Phillips, Meisenzahl, Eva M., McGorry, Patrick D., Andrea Mechelli, Koutsouleris, Nikolaos, Yung, Alison R.; id_orcid, Mechelli, Andrea, Yung, Alison R., Stefania Tognin, Borgwardt, Stefan J., Nikolaos Koutsouleris, Yung, Alison R, Riecher-Roessler, Anita, Stone, James; id_orcid, Meisenzahl, Eva M, Wood, Stephen J, Phillips, Lisa J., Woolley, James, Alison R. Yung, Valli, Isabel, Velakoulis, Dennis, Dennis Velakoulis, Stone, James M., Christos Pantelis, Tognin, Stefania; id_orcid, McGorry, Patrick D, Patrick D. McGorry, Phillips, Lisa J, Stephen J. Wood, Riecher-Rössler, Anita, Stefan J. Borgwardt, Philip McGuire   +42 more
core   +1 more source