Results 61 to 70 of about 54,150 (315)

Neuroanatomical abnormalities that predate the onset of psychosis : a multicenter study [PDF]

open access: yes, 2011
People experiencing possible prodromal symptoms of psychosis have a very high risk of developing the disorder, but it is not possible to predict, on the basis of their presenting clinical features, which individuals will subsequently become psychotic ...
James M. Stone   +42 more
core   +1 more source

Hope in primary caregivers' experience of first episode psychosis [PDF]

open access: yes, 2010
Introduction: Primary caregivers provide essential care and support to people with psychosis and are often key players within recovery. The recovery model and an expanding research literature suggest that the concept of hope is an important factor in ...
Miller, Jason Michael
core  

The influence of trial-by-trial feedback on trust in health, first-episode and chronic psychosis [PDF]

open access: yes, 2022
Trust is crucial to establishing reciprocal, positive social interactions and seems to be compromised in psychosis. The trust game offers methods to assess an individual’s trust responses to trust-reciprocating, positive feedback.
Wichmann, Rune J.   +3 more
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Clozapine prescribing during follow-up of a first-episode psychosis cohort

open access: yesEuropean Psychiatry, 2021
Introduction Of those with schizophrenia, one third develop treatment-resistant illness. Nearly 60% of these benefit from clozapine- the only antipsychotic medication licensed in this group.
R. Rowntree   +7 more
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

The Evaluation and Treatment of First-episode Psychosis [PDF]

open access: yesSchizophrenia Bulletin, 1997
A first episode of psychosis is a traumatic experience for patients and families. At the time of initial evaluation, the differential diagnosis should include a broad range of neurological, general medical, and psychiatric conditions. Methodological advances in operationally defining illness onset, "offset," and remission have allowed more careful ...
B B, Sheitman   +4 more
openaire   +2 more sources

Cognitive clusters in first-episode psychosis

open access: yesSchizophrenia Research, 2021
Impairments in a broad range of cognitive domains have been consistently reported in some individuals with first-episode psychosis (FEP). Cognitive deficits can be observed during the prodromal stage. However, the course of cognitive deficits is still unclear.
Amoretti S.   +20 more
openaire   +9 more sources

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc   +7 more
wiley   +1 more source

Ethnic variations in compulsory detention and hospital admission for psychosis across four UK Early Intervention Services

open access: yes, 2014
Substantial ethnic variations have been found in incidence, pathways to care and outcomes in psychosis. It is unknown whether these remain as marked in the presence of specialist Early Intervention Services (EIS) for psychosis.
Barnaby Major   +23 more
core   +1 more source

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