Results 51 to 60 of about 5,754,802 (309)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Quality Enhancement Themes: the First Year Experience. Curriculum Design for the First Year [PDF]

open access: yes, 2008
This report outlines the work and outcomes of a practice-focused development project 'Curriculum design for the first year'. The project was one of nine funded by the Quality Assurance Agency for Higher Education (QAA) under the First-Year Experience ...
Bovill, C., Bulley, C., Morss, K.
core  

Motivation, Optimal Experience and Flow in First Year Computing Science [PDF]

open access: yes, 2016
We examine the concept of motivation from the perspective of Self Determination Theory and give a brief overview of relevant results. We also consider the optimal state known as "Flow" and give an account of its conceptualisation in the theory due to ...
Cajander, Å   +4 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Importance of Empathy

open access: yesStudent Success
Dr Ella Kahu – The Importance of Empathy (2019 First Year Experience Learning and Teaching Forum, University of the Sunshine Coast, Australia) 2.10 minutes.
Ella Kahu
doaj   +1 more source

A Second Life First Year Experience

open access: yesJournal For Virtual Worlds Research, 2010
Learning experiences within Multi User Virtual Environments (MUVE’s) focus on discovery and active experiences and provide many opportunities to support multicultural learners. Virtual worlds have the potential to become meaningful, highly sophisticated tools for educators and students, and it is timely to consider how educators can move from the ...
Paul Penfold, Peter Duffy
openaire   +2 more sources

National research on the postgraduate student experiences:Case presentation on career development and employability (Volume 3 of 3) [PDF]

open access: yes, 2016
Also titled: First year postgraduate student experience "This is volume three of three volumes of case studies to enhance the postgraduate student experience.
Bannatyne, Amy Jean   +8 more
core  

First year engineering mathematics: the London South Bank University experience [PDF]

open access: yes, 2010
This short article describes an innovative approach to teaching mathematics to first year undergraduates on a variety of B. Eng. courses offered in the Faculty of Engineering, Science and Built Environment (FESBE) of London South Bank University (LSBU)
Crisan, C   +3 more
core   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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