Assessment of First Aid Knowledge at Different Stages of Education. [PDF]
García-Blaya JÁ +2 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Motivations, challenges, and benefits of first aid knowledge popularization volunteerism among undergraduate medical students: a qualitative study. [PDF]
Huang R, Li S, Guo Y, Yang X, Zhang B.
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Analyzing first aid in textbooks used by non-medical and paramedical students in Nepal: A need of further attention for snakebite management! [PDF]
Pandey DP, Khanal BP, Sapkota H.
europepmc +1 more source
Digital tool for childhood first aid: app for professionals and caregivers
Adriana Dall’Asta Pereira +5 more
openalex +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A comprehensive review of the dissemination and training of safety and first aid skills among early childhood educators. [PDF]
Wang X, Qiao T, Chang J, Ye P.
europepmc +1 more source
First Aid in Tamale Metropolitan Basic Schools, Ghana (Who Is Responsible?)
Zakaria Shanunu
openalex +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source

