Results 111 to 120 of about 246,572 (299)
The Accessible Toilet Design Resource [PDF]
, 2007 This Accessible Toilet Design Resource has been produced from new primary research carried out within VivaCity 2020, a large university-based research consortium that is developing tools and resources to support the design of socially inclusive cities ...
Bichard, Jo-Anne +2 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Nose cone mounted heat resistant antenna Patent [PDF]
, 1968 Nose cone mounted heat resistant antenna comprising plurality of adjacent layers of silica not introducing paths of high thermal conductivity through ablative ...
Dorne, A., Shube, E. E.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Descarga mássica de lote impermeabilizado: análise de first flush, eficiências e estimativa de carga [PDF]
Revista DAEO first flush (FF) é uma importante caracterização para controle da poluição decorrente do escoamento superficial direto (ESD). A ideia é que grande Urban drainage, First flush, Sediment transport parte da poluição transportada pelo ESD concentra-se nos ...
Ademir Paceli Barbassa +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Efficient simulation of view synchrony [PDF]
, 2012 This report presents an algorithm for efficiently simulating view synchrony, including failure-atomic total-order multicast in a discrete-time event simulator. In this report we show how a view synchrony implementation tailored to a simulated environment
Drejhammar, Frej, Haridi, Seif
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
, 1983 Manure handling is one of the most unappreciated chores associated with livestock enterprises. It is also the most difficult problem to solve in a totally satisfactory manner because physical characteristics of manure usually change with the daily ...
Cullum, Robert F.
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