Results 91 to 100 of about 248,175 (294)

ret2spec: Speculative Execution Using Return Stack Buffers

, 2018
Speculative execution is an optimization technique that has been part of CPUs for over a decade. It predicts the outcome and target of branch instructions to avoid stalling the execution pipeline.
Acıiccmez Onur, Aciiccmez Onur, Evtyushkin Dmitry, Fogh Anders, Gruss Daniel, Kocher Paul, Kohlbrenner David, Lipp Moritz, Maisuradze Giorgi, Maisuradze Giorgi, Maisuradze Giorgi, Song Chengyu   +11 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Development of a fabricated first-flush rainwater harvested technology to meet up the freshwater scarcity in a South Asian megacity, Dhaka, Bangladesh. [PDF]

Heliyon, 2023
Jamal AHMSIM, Tarek YA, Siddique MAB, Shaikh MAA, Debnath SC, Uddin MR, Ahmed S, Akbor MA, Al-Mansur MA, Islam ARMT, Khan R, Moniruzzaman M, Sultana S.   +12 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Occurrence and ecological risk of PAHs in urban road runoff in Beijing

Water Science and Technology
The occurrence and ecological risks of 16 polycyclic aromatic hydrocarbons (PAHs) in different types of urban road runoff in Beijing during two typical rainfall events were studied.
Xiaoran Zhang, Hongming Ji, Lei Yan, Junfeng Liu, Shiyu Wang, Ziyang Zhang, Chaohong Tan, Haiyan Li, Yuansheng Hu   +8 more
doaj   +1 more source

Who Put the P in Policy? The reality of guidelines and legislation in the design of the accessible toilet. [PDF]

, 2007
2-4 April ...
Bichard, J, Hanson, J
core  

Statistically-secure ORAM with $\tilde{O}(\log^2 n)$ Overhead

, 2013
We demonstrate a simple, statistically secure, ORAM with computational overhead $\tilde{O}(\log^2 n)$; previous ORAM protocols achieve only computational security (under computational assumptions) or require $\tilde{\Omega}(\log^3 n)$ overheard.
B. Pinkas, C. Gentry, D.L. Eager, E. Shi, I. Damgård, M. Maas, M. Mitzenmacher, M. Mitzenmacher, M. Mitzenmacher, N.D. Vvedenskaya, O. Goldreich, P. Lezaud, S. Lu   +12 more
core   +1 more source

Corrigendum to "Development of a fabricated first-flush rainwater harvested technology to meet up the freshwater scarcity in a South Asian megacity, Dhaka, Bangladesh" [Heliyon 9 (1) (January 2023) Article e13027]. [PDF]

Heliyon, 2023
Jamal AHMSIM, Tarek YA, Siddique MAB, Shaikh MAA, Debnath SC, Uddin MR, Ahmed S, Akbor MA, Al-Mansur MA, Islam ARMT, Khan R, Moniruzzaman M, Sultana S.   +12 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Non-concealed placebo treatment for menopausal hot flushes: Study protocol of a randomized-controlled trial

Trials, 2019
Background Beneficial effects of placebos are high in double-blind hot flush trials. Studies in various conditions suggest that honestly prescribed placebos may elicit symptom improvement. Objective To determine whether open label placebo (OLP) treatment
Yiqi Pan, Ramona Meister, Bernd Löwe, Anne Winkelmann, Ted J. Kaptchuk, Kai J. Buhling, Yvonne Nestoriuc   +6 more
doaj   +1 more source