Results 111 to 120 of about 248,175 (294)
Environmental sampling to assess the bioburden of Mycobacterium avium subspecies paratuberculosis in drylot pens on California dairies. [PDF]
, 2019 Mycobacterium avium subspecies paratuberculosis (MAP) is a bacterium that can cause substantial economic losses in infected dairy herds due to reduced milk production and increased cow-replacement costs.
Adaska, John M +4 more
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Characteristics of particle-associated PAHs in a first flush of a highway runoff
Water Science and Technology, 2006 Runoff monitoring of six rainfall events was carried out in a highway, Winterthur, Switzerland focusing on first flush (runoff volume up to 2.88 mm). Six runoff events were used to investigate the characteristics of particle-associated PAHs in first flush.
Aryal, R. K. +3 more
openaire +5 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Bioaerosol concentrations generated from toilet flushing in a hospital-based patient care setting
Antimicrobial Resistance and Infection Control, 2018 Background In the United States, 1.7 million immunocompromised patients contract a healthcare-associated infection, annually. These infections increase morbidity, mortality and costs of care.
Samantha D. Knowlton +5 more
doaj +1 more source
Heat transfer and pressure measurements and comparison with prediction for the SSME two-stage turbine [PDF]
Time averaged Stanton number and surface pressure distributions are reported for the first stage vane row, the first stage blade row, and the second stage vane row of the Rocketdyne Space Shuttle Main Engine (SSME) two-stage fuel-side turbine.
Dunn, M. G., Kim, J.
core +1 more source
Analysis of first flush to improve the water quality in rainwater tanks
Water Science and Technology, 2010 Although most Australians receive their domestic supply from reticulated mains or town water, there are vast areas with very low population densities and few reticulated supplies. In many of these areas rainwater collected in tanks is the primary source of drinking water.
B, Kus +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Effects of Crust Ingestion on Mixer Pump Performance in Tank [PDF]
, 1999 In August 1999, a workshop was held at Pacific Northwest National Laboratory to discuss the effects of crust ingestion on mixer pump performance in Hanford Waste Tank 241-SY-101.
Brennen, C. E. +2 more
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