Results 71 to 80 of about 13,718,597 (288)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Occurrence and ecological risk of PAHs in urban road runoff in Beijing
Water Science and TechnologyThe occurrence and ecological risks of 16 polycyclic aromatic hydrocarbons (PAHs) in different types of urban road runoff in Beijing during two typical rainfall events were studied.
Xiaoran Zhang +8 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
[Causes and differential diagnosis of flush.]
, 2013 International audience: The flush is a transient and recurrent erythema of the upper region of the body, due to a sudden arterial dilatation. First, physicians should confirm the flush and ascertain the location and timing of skin manifestations.
Lecornet-Sokol, E. +7 more
core +1 more source
Research on the Time Course of River Water Quality with Runoff in Urban Area
Renmin Zhujiang, 2020 Deterioration of river water quality during rainfall is a difficult problem for water environment treatment,and it is of great significance to study its change rules during rainfall.Taking the canal area of Guangzhou-Shenzhen Railway in Guangzhou Liede ...
LIU Zhijun +3 more
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Characterisation of First Flush for Rainwater Harvesting Purposes in Buildings
The objective of this research was to assess the first flush of rainwater harvested from a fibre–cement roof in southern Brazil. Runoff samples were collected for quantifying pH, total suspended solids, turbidity, conductivity, apparent colour ...
Jéssica Kuntz Maykot +2 more
core +1 more source
HydrologyMitigating nonpoint source pollution from stormwater runoff demands effective strategies for treating the first flush depth. Whether through off-stream storage or pass-through treatment devices, designing diversion structures and filtering materials is ...
David C. Froehlich
doaj +1 more source