Results 61 to 70 of about 13,255,053 (283)

Behaviour of Flush End-Plate Connection for Perforated Section [PDF]

Engineering Heritage Journal, 2017
This paper presents the study on the behaviour of the beam to column connection by using flush end plate connection for I-beam steel section with perforation. Moment rotation and failure pattern of flush end plate connection for perforated section were
Fatimah , Nurfarhah , Lai Chun
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Mass Loading of First Flush Pollutants with Treatment Strategy Simulations

, 2005
“First flush” is a term for the initial period of stormwater discharge from a storm event. Conventional thinking is that the first flush exhibits high pollutant concentrations. The existence of a first flush in highway runoff has been documented through
Michael K. Stenstrom, Masoud Kayhanian
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The potential contribution of riparian vegetation in non-point source pollution control during rainfall events in a tropical urban watershed [PDF]

RBRH
The presence of riparian vegetation can reduce the transport of sediments into receiving water bodies from surface runoff during rainfall events. However, this process is still overlooked in tropical watersheds, limiting the capacity of managers and ...
Cecilia Loretti de Paiva, João Miguel Merces Bega, Karen Tavares Zambrano, Davi Gasparini Fernandes Cunha   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

First flush effect from vegetated roofs during simulated rain events

, 2008
in UndeterminedVegetated roofs are becoming increasingly popular in urban environments. Still, several aspects of their influence on various urban infrastructures are not sufficiently investigated, including the roofs' influence on runoff water quality ...
Bengtsson, Lars, Jinno, Kenji, Czemiel Berndtsson, Justyna   +2 more
core   +2 more sources

A Modified Rational Method Approach for Calculating First Flush Design Flow Rates to Mitigate Nonpoint Source Pollution from Stormwater Runoff

Hydrology
Mitigating nonpoint source pollution from stormwater runoff demands effective strategies for treating the first flush depth. Whether through off-stream storage or pass-through treatment devices, designing diversion structures and filtering materials is ...
David C. Froehlich
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source