Results 41 to 50 of about 5,672,036 (294)

The effects of teacher feedback on multiple-draft compositions in ESL classrooms [PDF]

open access: yes, 2007
Teacher feedback plays a significant role in helping ESL learners acquire the writing skills. However, many research findings indicated that feedback on single draft essays does not help ESL learners much in improving the essays because these learners ...
Mohamad, Faizah, Othman, Shamshad Begham
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The modality constituent : a neglected area in the study of first language acquisition [PDF]

open access: yes, 1978
Studies of syntax in first language acquisition have so far concentrated on the propositional side of the sentence, i.e. on the occurrence and interplay of semantic roles like agent, benefactive, objective, etc. and their syntactic expression.
Stephany, Ursula
core  

Language-Based Image Editing with Recurrent Attentive Models

open access: yes, 2018
We investigate the problem of Language-Based Image Editing (LBIE). Given a source image and a natural language description, we want to generate a target image by editing the source image based on the description.
Chen, Jianbo   +4 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Aristotle’s theory of language in the light of Phys. I.1 [PDF]

open access: yes, 2018
The main aim of my paper is to analyse Aristotle’s theory of language in the context of his Physics I.1 and via an analysis and an interpretation of this part of his Physics I try to show that (i) the study of human language (logos) significantly falls ...
Labuda, Pavol
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

A Linear First-Order Functional Intermediate Language for Verified Compilers

open access: yes, 2015
We present the linear first-order intermediate language IL for verified compilers. IL is a functional language with calls to a nondeterministic environment.
Hack, Sebastian   +2 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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