Results 11 to 20 of about 26,268,555 (308)

First-line treatment of acute lymphoblastic leukemia with pegasparaginase [PDF]

Biologics: Targets & Therapy, 2009
Riccardo Masetti, Andrea PessionPediatric Oncology and Hematology Unit “Lalla Seràgnoli”, University of Bologna, Bologna, ItalyAbstract: Acute lymphoblastic leukemia (ALL) accounts for almost 4000 cases annually in the ...
Riccardo Masetti, Andrea Pession
doaj   +2 more sources

Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer

Cancer Management and Research, 2010
Noemí Reguart1, Andrés Felipe Cardona2, Rafael Rosell31Medical Oncology Service, ICMHO, Hospital Clinic Barcelona, Barcelona, Spain; 2Clinical and Translational Oncology Group, Institute of Oncology, Fundación Santa Fe de
Noemí Reguart, Andrés Felipe Cardona, Rafael Rosell   +2 more
doaj   +1 more source

Unfinished first-line tuberculosis treatment in primary care in Indonesia [PDF]

Family Medicine & Primary Care Review, 2019
Background. Unfinished tuberculosis (TB) treatment has slowly but surely become an unexpected event in the disease’s development into drug-resistant TB.
Al Asyary, Yodi Mahendradhata
doaj   +2 more sources

Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia [PDF]

, 2021
BACKGROUND: Immune thrombocytopenia (ITP) is a rare autoimmune thrombocytopenia with associated bleeding risk and fatigue. Recommended first line ITP treatment is with high dose glucocorticoids but side effects, heterogeneous responses and high relapse ...
Talks, Kate, Bradbury, Charlotte A., Ingram, Jenny, Rayment, Rachel, Hill, Quentin, Bagot, Catherine, Pell, Julie, Kandiyali, Rebecca, Breheny, Katie, Evans, Gillian, Greenwood, Rosemary, Cooper, Nichola, Thomas, Ian, Bradbury, Charlotte A, Greenwood, R, Rachel Rayment, Katie Breheny, Catherine Bagot, Rebecca Kandiyali, Kate Talks, Quentin Hill, Rosemary Greenwood, Ian Thomas, Julie Pell, Charlotte A. Bradbury, Jenny Ingram, Gillian Evans, Nichola Cooper   +27 more
core   +1 more source

Cost-effectiveness of tenofovir instead of zidovudine for use in first-line antiretroviral therapy in settings without virological monitoring. [PDF]

, 2012
BACKGROUND: The most recent World Health Organization (WHO) antiretroviral treatment guidelines recommend the inclusion of zidovudine (ZDV) or tenofovir (TDF) in first-line therapy.
Alec Miners, Valentina Cambiano (146513), von Wyl Viktor, Phillips, Andrew N, Andrew N Phillips, Jens Lundgren, Valentina Cambiano, Silvia Bertagnolio, Pillay Deenan, Pillay, Deenan, Deenan Pillay (7888), Bertagnolio, Silvia, Miners Alec, Michael R. Jordan (146520), Cambiano, Valentina, von Wyl, Viktor, Viktor von Wyl, Phillips Andrew N., Jordan, Michael R, Cambiano Valentina, Miners, Alec, Bertagnolio Silvia, Lundgren Jens, Andrew N. Phillips (146556), Lundgren, Jens, Alec Miners (146534), Viktor von Wyl (146506), Silvia Bertagnolio (57174), Michael R Jordan, Deenan Pillay, Jens Lundgren (146550), Jordan Michael R.   +31 more
core   +2 more sources

Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia [PDF]

, 2007
Background: Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is effective, it might, however, be contraindicated in cases of severe liver dysfunction due to advanced liver metastases.
Moosmann, Nicolas, Schulz, Christoph, Laessig, Dorit, Michaely, Henrik Jakob, Heinemann, Volker   +4 more
core   +1 more source

First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis. [PDF]

, 2021
Biologicals, in combination with chemotherapy, are recommended as first-line treatment of metastatic colorectal cancer (mCRC); however, evidence guiding the appropriate management of older patients with mCRC is limited.
Vieitez, Jose Maria, Safont, Maria Jose, Yubero, Alfonso, Valladares-Ayerbes, Manuel, Massuti, Bartomeu, Ferreiro, Reyes, Gravalos, Cristina, Garcia-Alfonso, Pilar, Sastre, Javier, Muñoz, Andres, Gonzalez, Encarnacion, Alonso-Orduña, Vicente, Ortiz-Morales, Maria Jose, Aranda, Enrique, Abad, Albert, Manzano Mozo, Jose Luis, Carrato, Alfredo, Duran, Gema, Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD), Rivera, Fernando, Diaz-Rubio, Eduardo   +20 more
core   +1 more source

Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]

, 2003
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core   +1 more source

Immunological failure of first-line and switch to second-line antiretroviral therapy among HIV-infected persons in Tanzania: analysis of routinely collected national data. [PDF]

, 2015
OBJECTIVES: Rates of first-line treatment failure and switches to second-line therapy are key indicators for national HIV programmes. We assessed immunological treatment failure defined by WHO criteria in the Tanzanian national HIV programme. METHODS: We
Ramadhani, Angela, Vanobberghen, Fiona M, Mmbando, Donan, Wringe, Alison, Todd, Jim, Zaba, Basia, Kilama, Bonita   +6 more
core   +1 more source

First- and Second-Line Palliative Systemic Treatment Outcomes in a Real-World Metastatic Pancreatic Cancer Cohort

, 2022
Background: Metastatic pancreatic ductal adenocarcinoma (PDAC) is characterized by a poor survival rate, which can be improved by systemic treatment. Consensus on the most optimal first- and second-line palliative systemic treatment is lacking.
Creemers, G.J., Creemers, Geert-Jan, Besselink, M.G., Besselink, Marc G., Wilmink, Johanna W., Mohammad, N.H., Dijksterhuis, Willemieke P.M., Dijksterhuis, W.P.M., Wilmink, J.W., Creemers, Geert Jan, Dijksterhuis, Willemieke P. M., van Laarhoven, Hanneke W. M., Pijnappel, E.N., de Vos-Geelen, J., van Laarhoven, Hanneke W.M., Homs, Marjolein Y. V., de Vos-Geelen, Judith, de Groot, J.W.B., de Groot, Jan Willem B., van der Geest, Lydia G., Mohammad, Nadia Haj, van der Geest, L.G., van Laarhoven, H.W.M., Homs, Marjolein Y.V., Homs, M.Y.V., Pijnappel, Esther N.   +25 more
core   +1 more source