Results 31 to 40 of about 26,268,555 (308)

Obinutuzumab for the First-Line Treatment of Follicular Lymphoma

New England Journal of Medicine, 2017
Rituximab-based immunochemotherapy has improved outcomes in patients with follicular lymphoma. Obinutuzumab is a glycoengineered type II anti-CD20 monoclonal antibody. We compared rituximab-based chemotherapy with obinutuzumab-based chemotherapy in patients with previously untreated advanced-stage follicular lymphoma.We randomly assigned patients to ...
Marcus, Robert, Davies, Andrew, Ando, Kiyoshi, Klapper, Wolfram, Opat, Stephen, Owen, Carolyn, Phillips, Elizabeth, Sangha, Randeep, Schlag, Rudolf, Seymour, John F, Townsend, William, Trněný, Marek, Wenger, Michael, Fingerle-Rowson, Günter, Rufibach, Kaspar, Moore, Tom, Herold, Michael, Hiddemann, Wolfgang   +17 more
openaire   +3 more sources

First-line treatment choice by age at diagnosis.

, 2018
First-line treatment choice by age at diagnosis.
Kristiina Kananen (6054188), Kari Remes (6054176), Tiina M. Järvinen (256223), Marta Pisini (6054194), Mervi Putkonen (5774924), Frida Schain (291265), Tricia Dixon (6054200), Venla Terävä (6054185), Hanna Ollikainen (6054182), Päivi Castren-Kortegangas (6054191), Amy Leval (350406), Pekka Anttila (6054179), Felix Wahl (6054197), Raija Silvennoinen (3088212), Marjatta Sinisalo (210631)   +14 more
core   +1 more source

Treatment-free interval in months according to age, following first-line and subsequent lines of therapy.

, 2020
Treatment-free interval in months according to age, following first-line and subsequent lines of therapy.
Toby A. Eyre (8479401), Grant Vallance (6078815), Susan McLain-Smith (8479398), Sally Moore (6078818), Faye A. Sharpley (8479395), Jaimal Kothari (6078821), Karthik Ramasamy (795392), Faouzi Djebbari (6004379)   +7 more
core   +1 more source

Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]

, 2012
Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Zielinski, Christoph C., Neumann, Jens, Stintzing, Sebastian, Ocvirk, Janja, Heinemann, Volker, Kurteva, Galina, Jung, Andreas, Modest, Dominik P., Brodowicz, Thomas, Knittelfelder, Regina, Kirchner, Thomas, Papai, Zsuzsanna, Laubender, Ruediger P.   +12 more
core   +1 more source

Patterns of Tyrosine Kinase Inhibitor Utilization in Newly Treated Patients With Chronic Myeloid Leukemia: An Exhaustive Population-Based Study in France

Frontiers in Oncology, 2021
We analyzed demographic characteristics, comorbidities and patterns of treatment with tyrosine kinase inhibitors (TKIs) in a cohort of 3,633 incident cases of chronic myeloid leukemia (CML) identified across France from 1 January 2011 to 31 December 2014.
Marie Pajiep, Marie Pajiep, Cécile Conte, Françoise Huguet, Martin Gauthier, Fabien Despas, Fabien Despas, Maryse Lapeyre-Mestre, Maryse Lapeyre-Mestre   +8 more
doaj   +1 more source

Doxycycline: a first-line treatment for bullous pemphigoid? [PDF]

The Lancet, 2017
No description ...
Henry Grantham, Deborah D. Stocken, Nicholas Reynolds   +2 more
openaire   +5 more sources

European Registry on Helicobacter pylori Management: Effectiveness of First and Second-Line Treatment in Spain

Antibiotics, 2020
The management of Helicobacter pylori infection has to rely on previous local effectiveness due to the geographical variability of antibiotic resistance. The aim of this study was to evaluate the effectiveness of first and second-line H. pylori treatment
María Caldas, Ángeles Pérez-Aisa, Manuel Castro-Fernández, Luis Bujanda, Alfredo J. Lucendo, Luis Rodrigo, Jose M. Huguet, Jorge Pérez-Lasala, Javier Molina-Infante, Jesús Barrio, Luis Fernández-Salazar, Ángel Lanas, Mónica Perona, Manuel Domínguez-Cajal, Juan Ortuño, Blas José Gómez-Rodríguez, Pedro Almela, Josep María Botargués, Óscar Núñez, Inés Modolell, Judith Gómez, Rafael Ruiz-Zorrilla, Cristóbal De la Coba, Alain Huerta, Eduardo Iyo, Liliana Pozzati, Rosario Antón, Mercé Barenys, Teresa Angueira, Miguel Fernández-Bermejo, Ana Campillo, Javier Alcedo, Ramón Pajares-Villaroya, Marianela Mego, Fernando Bermejo, José Luis Dominguez-Jiménez, Llúcia Titó, Nuria Fernández, Manuel Pabón-Carrasco, Ángel Cosme, Pilar Mata-Romero, Noelia Alcaide, Inés Ariño, Tommaso Di Maira, Ana Garre, Ignasi Puig, Olga P. Nyssen, Francis Megraud, Colm O’Morain, Javier P. Gisbert   +49 more
doaj   +1 more source

Difficult to treat absence seizures in children: A single-center retrospective study

Frontiers in Neurology, 2022
ObjectivesThe aim of this study was to analyse the characteristics of typical absence seizures (AS), myoclonic AS and AS with eyelid myoclonia in children and to find associations between these characteristics and difficult to treat absence seizures ...
Samo Gregorčič, Jaka Hrovat, Neli Bizjak, Neli Bizjak, Zvonka Rener Primec, Zvonka Rener Primec, Tadeja Hostnik, Blaž Stres, Blaž Stres, Blaž Stres, Mirjana Perković Benedik, Mirjana Perković Benedik, Damjan Osredkar, Damjan Osredkar   +13 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Alternative First-line Malaria Treatment

Annals of African Medicine
Malaria is a disease affecting millions of people, especially in Africa, Asia, and South America, and has become a substantial economic burden. Because malaria is contracted through the bite of a mosquito vector, it is very challenging to prevent. Bed nets and insect repellents are used in some homes; others do not have or use them
Maafoh, Cassandra, Onyedibe, Kenneth
openaire   +2 more sources