Results 21 to 30 of about 26,268,555 (308)
Ibrutinib and Venetoclax for First-Line Treatment of CLL
New England Journal of Medicine, 2019 Ibrutinib, an inhibitor of Bruton's tyrosine kinase, and venetoclax, an inhibitor of B-cell lymphoma 2 protein, have been approved for patients with chronic lymphocytic leukemia (CLL). Preclinical investigations have indicated potential synergistic interaction of their combination.We conducted an investigator-initiated phase 2 study of combined ...
Kater, Arnon P. +2 more
openaire +7 more sources
MedComm, 2023 Pembrolizumab with cisplatin and 5‐fluorouracil showed survival benefit but relatively high occurrence of treatment‐related adverse events (TRAEs) for recurrent/metastatic oral squamous cell carcinoma (R/M OSCC). A more tolerable regime is needed.
Houyu Ju +9 more
doaj +1 more source
Steroids: First Line Treatment in Pediatrics
Canadian Respiratory Journal, 1995 The benefits derived from the use or inhaled steroids in pediatric asthma are reviewed in relation to the age of the patient, the delivery system and the compliance versus frequency of administration of these medications.
Sheldon Spier
doaj +1 more source
First-Line Treatment in Hypertension [PDF]
Drugs, 1990 Once-daily administration of perindopril 4mg has been compared with captopril 25mg twice daily, atenolol 50mg once daily or a combination of hydrochlorothiazide 50mg plus amiloride 5mg once daily in double-blind studies of patients with supine diastolic blood pressures between 95 and 125mm Hg.
openaire +4 more sources
Racial and Sex Differences in the Response to First-Line Antihypertensive Therapy
Frontiers in Cardiovascular Medicine, 2020 Objective: As compared to whites, the black population develops hypertension (HTN) at an earlier age, has a greater frequency and severity of HTN, and has poorer control of blood pressure (BP).
John S. Clemmer +2 more
doaj +1 more source
Optimizing the first-line fertility treatment
Gynecological Endocrinology, 2018 The objective of this study was to identify sperm score thresholds to achieve satisfactory intrauterine insemination (IUI) success rates according to the response to stimulation with clomiphene citrate (CC). To minimize the confounding effect of female age, we included only CC/IUI cycles of women ≤35 years old.
Mohamad, Irani +5 more
openaire +2 more sources
Moving beyond first-line treatment options for OCD [PDF]
Mental Health Clinician, 2022 OCD is characterized by obsessions and compulsions that cause distress, are time-consuming, and interfere with a patient's social, occupational, or other areas of functioning.
Chris Paxos, PharmD, BCGP, BCPS, BCPP
doaj +1 more source
Ocoxin as a complement to first line treatments in cancer [PDF]
International Journal of Medical Sciences, 2021 Chemotherapy and radiotherapy are the most frequent treatment for patients suffering from malignant progression of cancer. Even though new treatments are now being implemented, administration of these chemotherapeutic agents remains as the first line option in many tumor types. However, the secondary effects of these compounds represent one of the main
Benedicto García, Aitor +2 more
openaire +3 more sources
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
Case Reports in Dermatological Medicine, 2021 Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions ...
Walter Belda +2 more
doaj +1 more source
Treatment-free interval in the total cohort following first-line and subsequent lines of therapy.
, 2020 Treatment-free interval in the total cohort following first-line and subsequent lines of therapy.
Toby A. Eyre (8479401) +7 more
core +1 more source