Results 121 to 130 of about 3,505,401 (326)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

User perspective and higher cognitive task-loads influence movement and performance in immersive training environments

open access: yesBMC Biomedical Engineering, 2019
Background In virtual reality (VR) applications such as games, virtual training, and interactive neurorehabilitation, one can employ either the first-person user perspective or the third-person perspective to perceive the virtual environment; however ...
Juan Trelles Trabucco   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Visual perspective and the characteristics of mind wandering

open access: yesFrontiers in Psychology, 2013
When the mind wanders away from the here-and-now toward imaginary events, it typically does so from one of two visual vantage points ― a first-person perspective (i.e., the world is seen as it is in everyday life) or a third-person perspective (i.e., the
Brittany Marie Christian   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Dorholt: An Original Fairy Tale as a Study in Creative Fantasy [PDF]

open access: yes, 2014
This thesis presents a study in creative fantasy by detailing plans for an original novel with the purpose of entertaining, instructing, and encouraging young readers.
Conrad, Amy
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Considerations on the analytical perspective of first person, third person and the Self

open access: yesHYBRIS: Revista de Filosofía, 2011
Descartes and Kant were right to distinguish between the characteristics of the intelligibleworld in relation to sensitive and critical of such arguments as Dennett's thesis of physicalism to the other,Charles Taylor's theory is something that ...
Osvaldino Marra Rodriguez
doaj  

Beyond the Cartesian Self

open access: yesPhenomenology and Mind, 2016
I review a number of approaches that attempt to deal with the gap that seems to exist between first-person and third-person accounts of consciousness, and some of the conceptual, epistemological, and methodological issues that surround this distinction ...
Lynne Baker
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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