Results 101 to 110 of about 19,150,051 (295)

2006 Sesquicentennial Christmas Celebration Program and Play Script [PDF]

open access: yes, 2006
Morehead First Christian Church Sesquicentennial Christmas Celebration Program and Play script title First Christmas Voices from December 2 ...
First Christian Church (Morehead, Ky.)
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

170 Scaffolding Learning through Digital Play: Translating Theory to Practice

open access: yesJournal of Clinical and Translational Science
OBJECTIVES/GOALS: Scaffolding aids learning by gradually removing assistance to encourage independence (Bickhard, 2013; Gross, 2015). Mightier is a commercially available biofeedback game that fosters emotion regulation (ER) skill practice through play ...
Morgan D. Mannweiler   +2 more
doaj   +1 more source

Playing the MEV Game on a First-Come-First-Served Blockchain

open access: yes2024 IEEE International Conference on Blockchain and Cryptocurrency (ICBC)
13 pages, 5 ...
Burak Öz   +4 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

[Letter from the Fair Play for Cuba Committee to Lee Harvey Oswald, May 29, 1963 #1]

open access: yes, 1963
Photograph of the first page of a letter from the Fair Play for Cuba Committee to Lee Harvey Oswald, on May 29, 1963, enclosing his card and receipt, as well as information to help him start an FPCC chapter in New ...
Fair Play for Cuba Committee   +1 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Comparison of educational facilitation approaches for Grade R English Additional Language learning in rural Mpumalanga

open access: yesSouth African Journal of Education, 2014
The Early Childhood Development Manager in Mpumalanga is faced with the problem of providing evidence-based guidance of the best facilitation approach in the Grade R context. An investigation on the effect of facilitation, i.e.
P Moodley, A Kritzinger, B Vinck
doaj  

Designing for social interaction through physical play, movement and learning

open access: yes, 2008
This paper reports on two related but different developments in relation to designing for social interaction. It intends to compare and link together both a four years old international collaborative industrial design and manufacturing studio project ...
Novoa, Mauricio (R13411)
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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