Results 111 to 120 of about 19,150,051 (295)
, 1995 The right rest and leisure, to engage in play is usually missing from any discussions of children's rights. It is all too easy to fall into the trap of thinking only of those rights which are about protections; from poverty, from war and from abuse of ...
Shier, Harry, Hart, Roger, PLAY-TRAIN
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Who Plays First? Optimizing the Order of Play in Stackelberg Games with Many Robots
Robotics: Science and Systems XXWe consider the multi-agent spatial navigation problem of computing the socially optimal order of play, i.e., the sequence in which the agents commit to their decisions, and its associated equilibrium in an N-player Stackelberg trajectory game. We model this problem as a mixed-integer optimization problem over the space of all possible Stackelberg ...
Haimin Hu +5 more
openaire +4 more sources
[Letter from the Fair Play for Cuba Committee to Lee Harvey Oswald, May 29, 1963 #2]
, 1963 Photocopy of the first page of a letter from the Fair Play for Cuba Committee to Lee Harvey Oswald, on May 29, 1963, enclosing his card and receipt, as well as information to help him start an FPCC chapter in New ...
Fair Play for Cuba Committee +1 more
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Lekende skriving i frilek og rammelek på 1. trinn
Nordic Journal of Literacy ResearchTidligere forskning viser at lek kan være en meningsfull kontekst for skriving, og at skriving kan bidra til utvikling i leken. I denne studien har vi undersøkt hva som skjer når man kombinerer lek og skriving på 1. trinn.
Hedvig Flaten Lie, Anne Kathrine Hundal
doaj +1 more source
Commissioned by Play Wales, this extensive litertature review considers contemporary research into childhood studies, relevant policy studies, the relationship between playing and being well, children's play patterns and examples of interventions to ...
Tawil, Ben +2 more
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source