Results 51 to 60 of about 546,644 (306)

Fiscal institutions and fiscal performance [PDF]

, 2021
Η δημοσιονομική απειθαρχία και η μεροληψία των μακροοικονομικών προβλέψεων έχουν αυξήσει το ενδιαφέρον για τη δημιουργία δημοσιονομικών θεσμών (εθνικοί δημοσιονομικοί κανόνες, ανεξάρτητα δημοσιονομικά συμβούλια). Μετά την πρόσφατη οικονομική κρίση, η ΕΕ ενίσχυσε την δημοσιονομική της διακυβέρνηση με ποικίλους τρόπους με αποτέλεσμα την επίτευξη βιώσιμων
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

La administración de la bula de la Santa Cruzada en Nueva España (1547-1659)

Historia Mexicana El Colegio de México, 2013
La bula de la Santa Cruzada constituyó uno de los ingresos más originales de la Real Hacienda. Se trataba de las limosnas que aportaban los fieles para obtener indulgencias, exenciones de ayunos y otros privilegios espirituales y, por tanto, de una renta
María del Pilar Martínez López-Cano
doaj  

THE SELECTION OF OBJECTIVES BY FISCAL POLITICS [PDF]

Annals of the University of Oradea: Economic Science, 2010
The multitude of fiscal politics` objectives supposes a rational and a well-informed selection of them. Fiscal politics handle specific instruments and levers , producing effects which are hard enough to be quantified and reactions, which most of the ...
Morar Ioan Dan
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

ANALYZING THE IMPACT OF SOME FISCAL AND MONETARY POLICIES IN THE VALUE OF AGRICULTURAL OUTPUT IN SELECTED ARAB COUNTRIES FOR THE PERIOD (1990-2010) COMPARATIVE STUDY [PDF]

Mesopotamia Journal of Agriculture, 2018
The research aims to identify some of the effects of fiscal and monetary policies in the value of agricultural output in selected Arab countries during the period (1990-2010). It has become necessary to know the role of fiscal and monetary policies tools
Ahmed Al-Mshhdani
doaj   +1 more source

Fiscal crises [PDF]

Journal of International Money and Finance, 2017
A key objective of fiscal policy is to maintain the sustainability of public finances and avoid crises. Remarkably, there is very limited analysis on fiscal crises. This paper presents a new database of fiscal crises covering different country groups, including low-income developing countries (LIDCs) that have been mostly ignored in the past. Countries
Kerstin Gerling, Paulo Medas, Tigran Poghosyan, Juan Farah-Yacoub, Yizhi Xu   +4 more
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Policy lags and exchange rate dynamics in Nigeria: Any evidence?

Jurnal Ekonomi Pembangunan, 2020
The study investigates policy lags and exchange rate dynamics in Nigeria. The downswing in the Nigerian economy attributed to recurring exchange rate fluctuations justifies this empirical investigation.
Ayinde Taofeek Olusola
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source