Results 71 to 80 of about 370,835 (304)
Revista de Derecho, 2020 En el presente trabajo realizamos un repaso de las modificaciones introducidas por la Ley de Urgente Consideración en el concepto de legítima defensa. Referimos especialmente a las presunciones establecidas por la nueva redacción así como el alcance de ...
Alejandra Domínguez +1 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Impact of Fiscal Decentralization on Economic Growth in the Districts of Nepal [PDF]
, 2014 This paper focuses on the evolving pattern of fiscal decentralization and its impact on the growth of per capita GDP of the districts in Nepal. The dependent variable is the growth of the per capita district agricultural GDP, which is, used as a proxy ...
Devkota, K. L.
core +1 more source
Fiscal Decentralization And Fiscal Performance [PDF]
, 2005 A resurgence of recent interest in fiscal federalism has been a source of concern among macroeconomic stabilization experts. They argue that a decentralized fiscal system poses a threat to macroeconomic stability as it is incompatible with prudent monetary and fiscal management.
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Fiscal Stimulus and Fiscal Sustainability
, 2017 The Great Recession and the Global Financial Crisis have left many developed countries with low interest rates and high levels of public debt, thus limiting the ability of policymakers to fight the next recession. Whether new fiscal stimulus programs would be jeopardized by these already heavy public debt burdens is a central question.
Alan Auerbach, Yuriy Gorodnichenko
openaire +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Kebijakan Perpajakan di Indonesia untuk Kemudahan Ekonomi saat Masa Pandemi Covid-19
JAKP (Jurnal Administrasi dan Kebijakan Publik), 2020 This research is aimed at discussing various policies on providing tax incentives offered by the Indonesian government to reduce the economic uncertainty impact caused by the pressure caused by the co-19 pandemi.
Maria R.U.D. Tambunan
doaj
Fiscal Mechanism of Unshadowing of the Economy of Ukraine
Наукові записки НаУКМА: Економічні науки, 2018 Under current circumstances, the imperfect conditions of economic activity, which are formed in the country, have a significant influence on the macroeconomic situation.
Olena Bazilinska, Natalia Panchenko
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source