Results 61 to 70 of about 546,644 (306)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

FISCAL RULES IN THE LIGHT OF THE FISCAL CRISIS

open access: yesEkonomia i Prawo, 2012
The article presents the essence and the meaning of the fiscal rules of the budgetary policy with particular emphasis on the period of financial crisis since 2008. The author presets the fiscal rules (criteria) in the European Union and national solutions.
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

NOVEDOSA TENDENCIA JURISPRUDENCIAL COLOMBIANA SOBRE RESPONSABILIDAD DEL ESTADO POR ACTOS TERRORISTAS

open access: yesProlegómenos, 2010
La Jurisprudencia del Consejo de Estado comienza a mostrar una tendencia novedosa y muy criticada, en materia de declaratoria de responsabilidad del Estado por actos de terrorismo.
Yolanda Margaux Guerra
doaj  

A note on inflation, unemployment and economic growth

open access: yesPSL Quarterly Review, 2014
Although even before the end of World War II the world was preparing itself to fight a relapse into stagnation, the harrowing role inflation was to have as a constant in the post-war economic scene was scarcely perceived.
G. MAGNIFICO
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

ANCHORING FISCAL EXPECTATIONS [PDF]

open access: yes
In this lecture, I argue that there are remarkable parallels between how monetary and fiscal policies operate on the macro economy and that these parallels are sufficient to lead us to think about transforming fiscal policy and fiscal institutions as ...
Eric M. Leeper
core   +2 more sources

Indicadores fiscales

open access: yesLecturas de Economía, 2010
Indicadores.
Diana María Cardona, Rodrigo Taborda
openaire   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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