Results 51 to 60 of about 2,341,935 (307)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
EUROPEAN MODELS OF SOLUTION TO THE PUBLIC DEBT PROBLEM: WHAT SHOULD UKRAINE CHOOSE [PDF]
European Vector of Economic DevelopmentThe article is devoted to the analysis of Ukraine’s debt challenges in the conditions of a full-scale war and in the period of post-war recovery. Despite significant external financial pressure and the growth of public debt to critically high values ...
Anatolii O. Zadoia
doaj +1 more source
Fiscal Federalism and the War on Drugs
, 2003 In 2000, 34% of federal defendants were prosecuted for drug offenses despite the fact that all states had statutes prohibiting these offenses. According to Fiscal Federalism, the national government should have a role in these prosecutions if there are inter-jurisdictional positive externalities for drug convictions.
openaire +2 more sources
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
ClíoWithin the parameters of descriptive methodology based on data from documentary sources, the objective of this research was to analyze fiscal frameworks in the 21st century with a critical focus on fiscal policy and private sector development in Ukraine
Tetyana Medynska +3 more
doaj +1 more source
Monetary and Fiscal Policy Interactions in the Post-war U.S
IMF Working Papers, 2010 A New Keynesian model allowing for an active monetary and passive fiscal policy (AMPF) regime and a passive monetary and active fiscal policy (PMAF) regime is fit to various U.S. samples from 1955 to 2007. Data in the pre-Volcker periods strongly prefer an AMPF regime, but the estimation is not very informative about whether the inflation coefficient ...
Susan S. Yang, Nora Traum
openaire +2 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The fiscal role of conscription in the US World War II effort [PDF]
I consider the role of conscription as a fiscal shock absorber in times of war. Conscription of military personnel allows the fiscal authority to minimize wartime government expenditure, and hence, minimize tax distortions associated with war finance.
Siu, Henry
core
Fiscal (Un)Sustainability in Practice: Local Government Finance in Visegrad Economies
Comparative Economic ResearchThe objective of this study is to evaluate the fiscal sustainability of Local Government Units (LGUs) in the Visegrad Group economies (Czechia, Hungary, Poland, and Slovakia; the V4), focusing on three key hypotheses: (1) LGUs in the V4 are involved in ...
Tomasz Uryszek +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source