Results 111 to 120 of about 1,198,477 (317)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Biennial report of Oregon Department of Fish and Wildlife to the Governor and the Sixty-First Legislative Assembly: 1979-1980 [PDF]

open access: yes
Report of the Oregon Fish and Game Commission’s transactions and operations for July 1, 1978-June 30, 1980. This report summarizes fish and game resources for the biennium, as well as research conducted and an outline of activities to educate the public ...
Oregon. Department of Fish and Wildlife
core  

2001 Accountability Report of the U. S. Fish and Wildlife Service [PDF]

open access: yes, 2014
The report reviews the accountability of the U.S. Fish and Wildlife Service during 2001.Shared Commitments To Conservation 2001 Accountability Report of the U. S. Fish and Wildlife Service U.S.
U.S. Fish & Wildlife Service
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Gagged and Doxed: Hacktivism’s Self-Incrimination Complex

open access: yesInternational Journal of Communication, 2016
The investigation, arrest, and conviction of a number of high-profile hacker-activists, or hacktivists, reveal the ways subjectivity is mobilized through processes of revelation and evasion.
Adam Fish, Luca Follis
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Biennial report of Oregon Department of Fish and Wildlife to the Governor and the Sixtieth Legislative Assembly: 1977-1978 [PDF]

open access: yes
Report of the Oregon Fish and Game Commission’s transactions and operations for July 1, 1976-June 30, 1978. This report summarizes fish and game resources for the biennium, as well as research conducted and an outline of activities to educate the public ...
Oregon. Department of Fish and Wildlife
core  

Big fish, little fish [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2016
Dirk J, Varelmann, Michael N, D'Ambra
openaire   +2 more sources

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