Results 131 to 140 of about 1,198,477 (317)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Staff Report to the Oregon Fish and Wildlife Commission: Disabled Clam Digger Permit [PDF]
This is an Oregon Department of Fish and Wildlife exhibit made before the April 26, 1995 meeting of the Oregon Fish and Wildlife Commission. The exhibit concerns the need for some disabled Oregonians to have assistance digging clams.
Golden, Jim +2 more
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Survey of Specific Fish Pathogens in Free-Ranging Fish from Devils Lake, North Dakota [PDF]
Several biological surveys have been performed at Devils Lake, North Dakota to provide timely information to resource managers to assess the potential for biota transfer from the operation of an outlet designed to carry water to the Sheyenne River.
Peters, Kenneth, Hudson, Crystal
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Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
The quality of crustacean aquatic products is affected by feed. Cholesterol (CHO), an essential element for crustacean growth, has been widely supplemented in diet, but its food quality regulation remains unclear.
Tingting Zhu +6 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Coast Range Subbasin Fish Management Plan [PDF]
A high priority of the Willamette Basin Fish Management Plan (ODFW 1988) was the preparation of plans for subbasins within the Willamette Basin. The Coast Range Subbasin Plan was developed to provide specific direction for management of the fish ...
Oregon. Department of Fish and Wildlife +4 more
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Producing fish and wildlife from Kansas ponds [1982] [PDF]
"January 1982."Descriptors: fishponds, pond management, ponds.Acknowledgements -- Inroduction -- Getting Started -- Technical Assistance -- Pond Permit Requirements -- Site Selection -- Watershed Size -- Land Use -- Topography -- Soils -- Pond Uses ...
Kansas Fish and Game Commission
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Fish Research Project, Oregon [PDF]
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.1983-At head of title, 1983-88: Annual progress report, Fish
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