Results 31 to 40 of about 2,404,049 (228)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Diadromous Fish Investigations, 2016: Anadromous Alosid Restoration and Evaluation [PDF]

open access: yes, 2017
Eight fishways on six New Hampshire (NH) coastal rivers were operated during the spring of 2016 to facilitate the passage of river herring (Alewife Alosa pseudoharengus and Blueback Herring Alosa aestivalis), American Shad Alosa sapidissima, and other ...
NH Fish & Game
core   +1 more source

Queerying activism through the lens of the sociology of everyday life [PDF]

open access: yes, 2018
The approaching 30th anniversary of the introduction of the 1988 Local Government Act offers an opportunity to reflect on the nature of lesbian, gay and bisexual (LGB) activism in Britain. The protests against its implementation involved some of the most
Almack, Kathryn   +2 more
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Auditory display for the blind [PDF]

open access: yes, 1974
A system for providing an auditory display of two-dimensional patterns as an aid to the blind is described. It includes a scanning device for producing first and second voltages respectively indicative of the vertical and horizontal positions of the scan
Fish, R. M.
core   +1 more source

Characteristic Polynomial Patterns in Difference Sets of Matrices

open access: yes, 2015
We show that for every subset $E$ of positive density in the set of integer square-matrices with zero traces, there exists an integer $k \geq 1$ such that the set of characteristic polynomials of matrices in $E-E$ contains the set of \emph{all ...
Björklund, Michael, Fish, Alexander
core   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

The Incidence and Cross Methods for Efficient Radar Detection

open access: yes, 2013
The designation of the radar system is to detect the position and velocity of targets around us. The radar transmits a waveform, which is reflected back from the targets, and echo waveform is received.
Fish, Alexander, Gurevich, Shamgar
core   +1 more source

Fish hemoglobins [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2007
Vertebrate hemoglobin, contained in erythrocytes, is a globular protein with a quaternary structure composed of 4 globin chains (2 alpha and 2 beta) and a prosthetic group named heme bound to each one. Having myoglobin as an ancestor, hemoglobin acquired the capacity to respond to chemical stimuli that modulate its function according to tissue ...
Souza, P. C. de   +1 more
openaire   +7 more sources

Home - About - Disclaimer - Privacy