Results 51 to 60 of about 2,729,373 (300)
Limits of Nature and Advances of Technology: What Does Biomimetics Have to Offer to Aquatic Robots?
Applied Bionics and Biomechanics, 2006 In recent years, the biomimetic approach has been utilized as a mechanism for technological advancement in the field of robotics. However, there has not been a full appreciation of the success and limitations of biomimetics.
F. E. Fish
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Z uszanowaniem od Autora: refleksje nad Austinem i Derridą
Er(r)go, 2001 This essay is concerned with Jacques Derrida's arguments promulgated in “Signature Event Context” which Fish confronts with J. L. Austin's views on performative language.
Stanley Fish
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Putting pharmaceuticals into the wider context of challenges to fish populations in rivers [PDF]
, 2014 The natural range of fish species in our rivers is related to flow, elevation, temperature, local habitat and connectivity. For over 2000 years, humans have altered to varying degrees the river habitat.
Andrew C. Johnson +7 more
core +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Incremental events in the construction of sambaquis, southeastern Santa Catarina.
Revista do Museu de Arqueologia e Etnologia, 2000 Moundbuilding is a cross-cultural phenomenon of nearly world-wide scope. In this article some of the moundbuilding processes related to the sambaquis (shellmounds) from the coast of Santa Catarina State, Brasil, are examined, focusing on field research ...
Suzanne K. Fish +3 more
doaj +1 more source
Content repositories and social networking : can there be synergies? [PDF]
, 2008 This paper details the novel application of Web 2.0 concepts to current services offered to Social Scientists by the ReDReSS project, carried out by the Centre for e-Science at Lancaster University.
Dolby, Paul, Fish, Adrian
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source