Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Calibrating minimum counts and catch‐per‐unit‐effort as indices of moose population trend
Monitoring wildlife population trends often involves indices assumed to correlate in proportion to abundance. We used aerial count data and harvest statistics for moose (Alces alces) populations in 16 hunting districts of Montana, USA, spanning 32 years (
Nicholas J. DeCesare +7 more
doaj +1 more source
Dual Mode Logic—Design for Energy Efficiency and High Performance
The recently proposed dual mode logic (DML) gates family enables a very high level of energy-delay optimization flexibility at the gate level. In this paper, this flexibility is utilized to improve energy efficiency and performance of combinatorial ...
Itamar Levi, Alexander Fish
doaj +1 more source
Anadromous Fish Investigations, Year 2005 [PDF]
Seven department fish ladders on six coastal rivers were operated during the spring of 2005 to facilitate the passage of river herring, American shad, and other diadromous fish over dams.
NH Fish and Game
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Myth debunked: Keratinous pangolin scales do not contain the analgesic tramadol
Conservation plans aiming to reduce the threat of illegal wildlife trade increasingly recognize the need for multifaceted approaches that include both enhanced enforcement and demand reduction initiatives.
Rachel L. Jacobs +3 more
doaj +1 more source
Regional African stock markets indices
This paper presents an overview of the construction of regional indices for three of the four regions within Africa. The three indices are the EASDEX (for East Africa), the NADEX (for North Africa) and the WADEX (for West Africa).
T. Fish, N. Biekpe
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
TRIVALENT CHROMIUM (CR+3) IN DIETARY CARBOHYDRATE AND ITS EFFECT ON THE GROWTH OF COMMONLY CULTIVATED FISH [PDF]
Trivalent chromium (Cr+3) is an essential trace mineral for fish bio-physiological functions. Researches on Cr+3 in the form of organic compound indicated that the mineral affected the bio-activity of insulin, the blood glucose influx, and subsequently ...
Hastuti, Sri, Subandiyono, Subandiyono
core
Gender and innovation processes in integrated fish agri-food systems in Bangladesh and the Philippines: Insights from the CGIAR Research Program on FISH [PDF]
This FISH report provides insights on the interactions between gender norms, agency, and innovation in fish agri-food ...
Aregu, Lemlem +4 more
core

