Results 61 to 70 of about 1,467,566 (278)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Dual Mode Logic—Design for Energy Efficiency and High Performance
The recently proposed dual mode logic (DML) gates family enables a very high level of energy-delay optimization flexibility at the gate level. In this paper, this flexibility is utilized to improve energy efficiency and performance of combinatorial ...
Itamar Levi, Alexander Fish
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Fish Commission research briefs. Vol. 1, no. 1
These short reports are intended to inform the public, industry, and other interested parties of the current studies of the Commission's staff and the basis for conservation measures.
Oregon. Fish Commission
core +4 more sources
Calibrating minimum counts and catch‐per‐unit‐effort as indices of moose population trend
Monitoring wildlife population trends often involves indices assumed to correlate in proportion to abundance. We used aerial count data and harvest statistics for moose (Alces alces) populations in 16 hunting districts of Montana, USA, spanning 32 years (
Nicholas J. DeCesare +7 more
doaj +1 more source
Regional African stock markets indices
This paper presents an overview of the construction of regional indices for three of the four regions within Africa. The three indices are the EASDEX (for East Africa), the NADEX (for North Africa) and the WADEX (for West Africa).
T. Fish, N. Biekpe
doaj +1 more source
National fish, wildlife and plants climate adaptation strategy
The purpose of the National Fish, Wildlife and Plants Climate Adaptation Strategy is to inspire and enable natural resource administrators, elected officials, and other decision makers to take action to adapt to a changing climate.
National Fish, Wildlife and Plants Climate adaptation Partnership
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Seventy-five years of successful wildlife management is the remarkable legacy of the Pittman-Robertson Wildlife Restoration Act, and the cause of our 75th celebration. Along with the Dingell-Johnson Sport Fish Restoration Act, it is the foundation of the
U.S. Fish and Wildlife Service
core
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

