Results 51 to 60 of about 3,043,670 (297)

Content repositories and social networking : can there be synergies? [PDF]

open access: yes, 2008
This paper details the novel application of Web 2.0 concepts to current services offered to Social Scientists by the ReDReSS project, carried out by the Centre for e-Science at Lancaster University.
Dolby, Paul, Fish, Adrian
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Regional African stock markets indices

open access: yesSouth African Journal of Business Management, 2002
This paper presents an overview of the construction of regional indices for three of the four regions within Africa. The three indices are the EASDEX (for East Africa), the NADEX (for North Africa) and the WADEX (for West Africa).
T. Fish, N. Biekpe
doaj   +1 more source

TRIVALENT CHROMIUM (CR+3) IN DIETARY CARBOHYDRATE AND ITS EFFECT ON THE GROWTH OF COMMONLY CULTIVATED FISH [PDF]

open access: yes, 2016
Trivalent chromium (Cr+3) is an essential trace mineral for fish bio-physiological functions. Researches on Cr+3 in the form of organic compound indicated that the mineral affected the bio-activity of insulin, the blood glucose influx, and subsequently ...
Hastuti, Sri, Subandiyono, Subandiyono
core  

Putting pharmaceuticals into the wider context of challenges to fish populations in rivers [PDF]

open access: yes, 2014
The natural range of fish species in our rivers is related to flow, elevation, temperature, local habitat and connectivity. For over 2000 years, humans have altered to varying degrees the river habitat.
Andrew C. Johnson   +7 more
core   +3 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The Fish Funnel: A Trawl Modification to Reduce Fish Escapement [PDF]

open access: yes, 1989
In the Gulf of Mexico there is a need to assess the potential of underutilized fish resource stocks before a commercial fishery develops. Standard sampling trawls used in the Gulf are ineffective for sampling the resource, so larger, high opening, bottom
Taylor, Charles W., Workman, Ian K.
core  

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