Results 131 to 140 of about 779,549 (316)

Atoh1 is required for the formation of lateral line electroreceptors and hair cells, whereas FoxG1 represses an electrosensory fate

eLife
In electroreceptive jawed fishes and amphibians, individual lateral line placodes form lines of neuromasts on the head containing mechanosensory hair cells, flanked by fields of ampullary organs containing electroreceptors—modified hair cells that ...
Martin Minařík, Alexander S Campbell, Roman Franěk, Michaela Vazačová, Miloš Havelka, David Gela, Martin Pšenička, Clare VH Baker   +7 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Comprehensive multi-omics analysis uncovers potential risks of aged sperm on offspring development after short-term storage

BMC Biology
Background Recent studies have demonstrated that prolonged sperm storage adversely affects offspring through epigenetics, yet its broader effects on other molecular levels such as transcription and proteomics in progeny have been rarely explored. Results
Yu Cheng, Songpei Zhang, Sayyed Mohammad Hadi Alavi, Rigolin Nayak, Swapnil Gorakh Waghmare, Nururshopa Eskander Shazada, Deepali Rahi Roy, Zhijun Ma, Otomar Linhart, Zuzana Linhartová   +9 more
doaj   +1 more source

The effect of stocking density ratio of fish on water plant productivity in aquaponics culture system

, 2017
Yuli Andriani, Yayat Dhahiyat, Zahidah Zahidah, Irfan Zidni   +3 more
openalex   +1 more source

Optimal conditions and parameters verification of fish fillets muscle tissue biotransformation by bacterial starter cultures

, 2023
Elizaveta Vasilyevna Lavruhina, Nikita Yurievich zarubin, Olga Bredikhina, Alexandra Grinevich, А.В. Межонов   +4 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Increasing the Natural Productivity of Fish Ponds by Applying the IMTA Concept for Efficient Use of Natural Resources

Scientific Papers Animal Science and Biotechnologies
Aquaculture operates according to a principle of rational use of nature's trophic base, being in strict correlation with the biological period of growth and development of the fish stock in an area unit.
Mariana Cristina Arcade, Mioara Costache, Marinela Gancea, Carmen Georgeta Nicolae, Sorin Marian Drăguț   +4 more
doaj  

Functions of thyroid hormone signaling in regulating melanophore, iridophore, erythrophore, and pigment pattern formation in spotted scat (Scatophagus argus)

BMC Genomics
Background Spotted scat, a marine aquaculture fish, has variable body color development stages during their ontogenesis. However, the regulatory mechanism of body color patterns formation was poorly understood.
Yongguan Liao, Tong Han, Dongneng Jiang, Chunhua Zhu, Gang Shi, GuangLi Li, Hongjuan Shi   +6 more
doaj   +1 more source

Aquaculture Asia, Vol. 8, No. 1, pp.1-58, January-March 2003 [PDF]

, 2003
*Table of Contents* Sustainable Aquaculture Fertilization, soil and water quality management in small-scale ponds part II:Soil and water quality management S.

core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source