IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Gut-Derived Lactic Acid Bacteria, <i>Pediococcus pentosaceus</i>, Enhances Growth Performance and Resistance to Pathogenic <i>Vibrio harveyi</i> of Hatchery-Bred Milkfish (<i>Chanos chanos</i>) in Nursery Culture. [PDF]
Batilong LS +9 more
europepmc +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
A new lineage of <i>Ranavirus micropterus1</i> infects ornamental wrasses (<i>Macropharyngodon choati</i>) from the Great Barrier Reef and causes severe disease in captivity. [PDF]
Costa VA +6 more
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Detection of Bacterial Internalization in Lettuce (<i>Lactuca sativa</i>) Leaves Grown in Aquaponic Systems with Nile Tilapia (<i>Oreochromis niloticus</i>) Under Microbial Challenge. [PDF]
Jossefa AA +4 more
europepmc +1 more source
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Aeroponic and NFT system optimization for lettuce: effects of flow rate and nutrient source on water use efficiency, growth, and profitability. [PDF]
El-Demerdash DI +4 more
europepmc +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source

