Results 71 to 80 of about 167,181 (264)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Evaluation of Biofloc Technology Application on Water Quality and Production Performance of Red Tilapia Oreochromis sp. Cultured at Different Stocking Densities

Hayati Journal of Biosciences, 2012
This study evaluated the effect of biofloc technology (BFT) application on water quality and production performance of red tilapia Oreochromis sp. at different stocking densities. Three different fish densities were applied, i.e. 25, 50, and 100 fish/m3,
WIDANARNI, JULIE EKASARI, SITI MARYAM
doaj   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Stocking density during the initial grow-out phase of tambatinga in net pens

Ciência Rural, 2016
: The aim of this study was to determine the most adequate stocking density for tambatinga during the initial grow-out phase in net pens, considering fish growth, health, and financial aspects.
Ana Paula Oeda Rodrigues, Adriana Ferreira Lima, Patricia Oliveira Maciel, Patrícia Resplandes Rocha dos Santos, Roberto Manolio Valladão Flores, Adriano Prysthon da Silva   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The effect of fish density and tank size on the behavior of adult zebrafish: A systematic analysis. [PDF]

Front Behav Neurosci, 2022
Shishis S, Tsang B, Gerlai R.
europepmc   +1 more source

On the Influence of Density of Fish-eggs on their Hatching

NIPPON SUISAN GAKKAISHI, 1940
In order to know the influence of the density of fish-eggs on their hatching, experiments were carried out with the case where the medium water was replaced by the amount, inversely proportional to the density of eggs. The results may be summarized as follows: - (1) Generally speaking, the influence of density of eggs is not remarkable upon the ...
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Investigation of the pangas (Pangasianodon hypophthalmus) cultivation sustainability in cages at the Ratargul Freshwater Swamp Forest of Bangladesh

Aquaculture, Fish and Fisheries
Determining the most appropriate stocking density for a specific fish species in an ambient condition is essential for successful cage aquaculture in terms of profitability which is mainly governed by growth.
Mrityunjoy Kunda, Md. Abu Kawsar, Diponkor Adikari, Sakib Tahmid Rishan, Ahmed Harun‐Al‐Rashid, Debasish Pandit   +5 more
doaj   +1 more source

Interactive effects of triploidy induction and culture densities on growth performance and stress, immune, and metabolic responses in juvenile rainbow trout (Oncorhynchus mykiss)

Aquaculture Reports
This experiment aimed to evaluate the effects of triploidization and culture densities on the performance of rainbow trout. Juveniles (30.70 ± 1.04 g) were randomly stocked into 24 fiberglass tanks with a flow-through system.
Roghayeh Mahmoudi, Mahdi Naderi, Hakimeh Dopeikar, Seyed Ali Khorasaninasab, Seyed Hadi Seyedalhosseini   +4 more
doaj   +1 more source